Archives March 2025

Viquidil hydrochloride

Product Name :
Viquidil hydrochloride

Description:
Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity.

CAS:
52211-63-9

Molecular Weight:
360.88

Formula:
C20H25ClN2O2

Chemical Name:
3-[(3R,4R)-3-ethenylpiperidin-4-yl]-1-(6-methoxyquinolin-4-yl)propan-1-one hydrochloride

Smiles :
Cl.COC1=CC2=C(C=CN=C2C=C1)C(=O)CC[C@@H]1CCNC[C@@H]1C=C

InChiKey:
YUBRJAHSRSIPKX-LDXVYITESA-N

InChi :
InChI=1S/C20H24N2O2.ClH/c1-3-14-13-21-10-8-15(14)4-7-20(23)17-9-11-22-19-6-5-16(24-2)12-18(17)19;/h3,5-6,9,11-12,14-15,21H,1,4,7-8,10,13H2,2H3;1H/t14-,15+;/m0./s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity.|Product information|CAS Number: 52211-63-9|Molecular Weight: 360.88|Formula: C20H25ClN2O2|Chemical Name: 3-[(3R,4R)-3-ethenylpiperidin-4-yl]-1-(6-methoxyquinolin-4-yl)propan-1-one hydrochloride|Smiles: Cl.{{Fmoc-L-Trp(Boc)-OH} site|{Fmoc-L-Trp(Boc)-OH} {Amino Acid Derivatives}|{Fmoc-L-Trp(Boc)-OH} Technical Information|{Fmoc-L-Trp(Boc)-OH} Description|{Fmoc-L-Trp(Boc)-OH} supplier|{Fmoc-L-Trp(Boc)-OH} Autophagy} COC1=CC2=C(C=CN=C2C=C1)C(=O)CC[C@@H]1CCNC[C@@H]1C=C|InChiKey: YUBRJAHSRSIPKX-LDXVYITESA-N|InChi: InChI=1S/C20H24N2O2.{{Ferritin heavy chain/FTH1 Protein, Human} web|{Ferritin heavy chain/FTH1 Protein, Human} Biological Activity|{Ferritin heavy chain/FTH1 Protein, Human} References|{Ferritin heavy chain/FTH1 Protein, Human} custom synthesis|{Ferritin heavy chain/FTH1 Protein, Human} Epigenetics} ClH/c1-3-14-13-21-10-8-15(14)4-7-20(23)17-9-11-22-19-6-5-16(24-2)12-18(17)19;/h3,5-6,9,11-12,14-15,21H,1,4,7-8,10,13H2,2H3;1H/t14-,15+;/m0.PMID:32529926 /s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 15 mg/mL (41.57 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Viquidil hydrochloride (Quinotoxine hydrochloride) increases the cerebral blood flow in the rabbit considerably.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Nordihydrocapsaicin

Product Name :
Nordihydrocapsaicin

Description:
Nordihydrocapsaicin is a capsaicinoid analog and congener of capsaicin in chili peppers.

CAS:
28789-35-7

Molecular Weight:
293.40

Formula:
C17H27NO3

Chemical Name:
N-[(4-hydroxy-3-methoxyphenyl)methyl]-7-methyloctanamide

Smiles :
COC1=CC(CNC(=O)CCCCCC(C)C)=CC=C1O

InChiKey:
VQEONGKQWIFHMN-UHFFFAOYSA-N

InChi :
InChI=1S/C17H27NO3/c1-13(2)7-5-4-6-8-17(20)18-12-14-9-10-15(19)16(11-14)21-3/h9-11,13,19H,4-8,12H2,1-3H3,(H,18,20)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Nordihydrocapsaicin is a capsaicinoid analog and congener of capsaicin in chili peppers.{{Isradipine} MedChemExpress|{Isradipine} Calcium Channel|{Isradipine} Biological Activity|{Isradipine} In Vivo|{Isradipine} supplier|{Isradipine} Autophagy} |Product information|CAS Number: 28789-35-7|Molecular Weight: 293.40|Formula: C17H27NO3|Chemical Name: N-[(4-hydroxy-3-methoxyphenyl)methyl]-7-methyloctanamide|Smiles: COC1=CC(CNC(=O)CCCCCC(C)C)=CC=C1O|InChiKey: VQEONGKQWIFHMN-UHFFFAOYSA-N|InChi: InChI=1S/C17H27NO3/c1-13(2)7-5-4-6-8-17(20)18-12-14-9-10-15(19)16(11-14)21-3/h9-11,13,19H,4-8,12H2,1-3H3,(H,18,20)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Salinomycin} MedChemExpress|{Salinomycin} Wnt|{Salinomycin} NF-κB|{Salinomycin} Technical Information|{Salinomycin} Formula|{Salinomycin} manufacturer} |Shelf Life: ≥12 months if stored properly.PMID:31985940 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

[Gln8]-C517 (LH-RH), chicken

Product Name :
[Gln8]-C517 (LH-RH), chicken

Description:
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

CAS:
47922-48-5

Molecular Weight:
1154.23

Formula:
C54H71N15O14

Chemical Name:
(4S)-5-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-4-[(2S)-2-{2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamido]-5-oxopentanamide

Smiles :
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O

InChiKey:
WPKQYFUSPONRAT-BXXNOCLASA-N

InChi :
InChI=1S/C54H71N15O14/c1-28(2)18-37(49(78)64-36(13-15-43(55)72)54(83)69-17-5-8-42(69)53(82)59-24-44(56)73)63-46(75)25-60-47(76)38(19-29-9-11-32(71)12-10-29)65-52(81)41(26-70)68-50(79)39(20-30-22-58-34-7-4-3-6-33(30)34)66-51(80)40(21-31-23-57-27-61-31)67-48(77)35-14-16-45(74)62-35/h3-4,6-7,9-12,22-23,27-28,35-42,58,70-71H,5,8,13-21,24-26H2,1-2H3,(H2,55,72)(H2,56,73)(H,57,61)(H,59,82)(H,60,76)(H,62,74)(H,63,75)(H,64,78)(H,65,81)(H,66,80)(H,67,77)(H,68,79)/t35-,36-,37-,38-,39-,40-,41-,42-/m0/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ixekizumab} MedChemExpress|{Ixekizumab} Immunology/Inflammation|{Ixekizumab} Purity & Documentation|{Ixekizumab} Description|{Ixekizumab} manufacturer|{Ixekizumab} Epigenetics}

Shelf Life:
≥12 months if stored properly.{{TLQP-21} web|{TLQP-21} Agonist|{TLQP-21} Epigenetics|{TLQP-21} Purity & Documentation|{TLQP-21} In Vitro|{TLQP-21} supplier}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32750860

Additional information:
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.|Product information|CAS Number: 47922-48-5|Molecular Weight: 1154.23|Formula: C54H71N15O14|Chemical Name: (4S)-5-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-4-[(2S)-2-{2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]acetamido}-4-methylpentanamido]-5-oxopentanamide|Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O|InChiKey: WPKQYFUSPONRAT-BXXNOCLASA-N|InChi: InChI=1S/C54H71N15O14/c1-28(2)18-37(49(78)64-36(13-15-43(55)72)54(83)69-17-5-8-42(69)53(82)59-24-44(56)73)63-46(75)25-60-47(76)38(19-29-9-11-32(71)12-10-29)65-52(81)41(26-70)68-50(79)39(20-30-22-58-34-7-4-3-6-33(30)34)66-51(80)40(21-31-23-57-27-61-31)67-48(77)35-14-16-45(74)62-35/h3-4,6-7,9-12,22-23,27-28,35-42,58,70-71H,5,8,13-21,24-26H2,1-2H3,(H2,55,72)(H2,56,73)(H,57,61)(H,59,82)(H,60,76)(H,62,74)(H,63,75)(H,64,78)(H,65,81)(H,66,80)(H,67,77)(H,68,79)/t35-,36-,37-,38-,39-,40-,41-,42-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Sandramycin

Product Name :
Sandramycin

Description:
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity.

CAS:
100940-65-6

Molecular Weight:
1221.32

Formula:
C60H76N12O16

Chemical Name:
3-hydroxy-N-[(3R, 7S, 16S, 23R, 27S, 36S)-23-(3-hydroxyquinoline-2-amido)-8, 11, 28, 31-tetramethyl-2, 6, 9, 12, 15, 22, 26, 29, 32, 35-decaoxo-7, 27-bis(propan-2-yl)-5, 25-dioxa-1, 8, 11, 14, 21, 28, 31, 34-octaazatricyclo[34.4.0.0, ]tetracontan-3-yl]quinoline-2-carboxamide

Smiles :
CN1CC(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCC[C@H]2C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCC[C@H]2C(=O)NCC1=O

InChiKey:
WXIVYIYCEBUEHL-RTQGILJWSA-N

InChi :
InChI=1S/C60H76N12O16/c1-33(2)51-59(85)87-31-39(65-55(81)49-43(73)25-35-17-9-11-19-37(35)63-49)57(83)71-23-15-13-21-41(71)53(79)62-28-46(76)68(6)30-48(78)70(8)52(34(3)4)60(86)88-32-40(66-56(82)50-44(74)26-36-18-10-12-20-38(36)64-50)58(84)72-24-16-14-22-42(72)54(80)61-27-45(75)67(5)29-47(77)69(51)7/h9-12,17-20,25-26,33-34,39-42,51-52,73-74H,13-16,21-24,27-32H2,1-8H3,(H,61,80)(H,62,79)(H,65,81)(H,66,82)/t39-,40-,41+,42+,51+,52+/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity.|Product information|CAS Number: 100940-65-6|Molecular Weight: 1221.{{SMARCA2/4-IN-2} MedChemExpress|{SMARCA2/4-IN-2} PROTAC|{SMARCA2/4-IN-2} Activator|{SMARCA2/4-IN-2} Protocol|{SMARCA2/4-IN-2} Formula|{SMARCA2/4-IN-2} supplier} 32|Formula: C60H76N12O16|Chemical Name: 3-hydroxy-N-[(3R, 7S, 16S, 23R, 27S, 36S)-23-(3-hydroxyquinoline-2-amido)-8, 11, 28, 31-tetramethyl-2, 6, 9, 12, 15, 22, 26, 29, 32, 35-decaoxo-7, 27-bis(propan-2-yl)-5, 25-dioxa-1, 8, 11, 14, 21, 28, 31, 34-octaazatricyclo[34.4.0.0, ]tetracontan-3-yl]quinoline-2-carboxamide|Smiles: CN1CC(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCC[C@H]2C(=O)NCC(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)OC[C@@H](NC(=O)C2=NC3=CC=CC=C3C=C2O)C(=O)N2CCCC[C@H]2C(=O)NCC1=O|InChiKey: WXIVYIYCEBUEHL-RTQGILJWSA-N|InChi: InChI=1S/C60H76N12O16/c1-33(2)51-59(85)87-31-39(65-55(81)49-43(73)25-35-17-9-11-19-37(35)63-49)57(83)71-23-15-13-21-41(71)53(79)62-28-46(76)68(6)30-48(78)70(8)52(34(3)4)60(86)88-32-40(66-56(82)50-44(74)26-36-18-10-12-20-38(36)64-50)58(84)72-24-16-14-22-42(72)54(80)61-27-45(75)67(5)29-47(77)69(51)7/h9-12,17-20,25-26,33-34,39-42,51-52,73-74H,13-16,21-24,27-32H2,1-8H3,(H,61,80)(H,62,79)(H,65,81)(H,66,82)/t39-,40-,41+,42+,51+,52+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Opipramol} MedChemExpress|{Opipramol} Sigma Receptor|{Opipramol} Biological Activity|{Opipramol} In Vivo|{Opipramol} supplier|{Opipramol} Epigenetics} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Sandramycin has antimicrobial activity wtih MIC values of 0.PMID:32329329 024 μg/mL, 0.012 μg/mL, 0.012 μg/mL, 0.098 μg/mL, 0.024 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Bacillus subtilis (Rec+) A22508-2, B. subtilis (Rec-) A22509-2-2, Staphylocccus aureus 209P-A9497, S. aureus (echinomycin-resistant) A9628, Streptococcus faecalis A96 1 1, Escherichia coli A151 19 and E. coli (actinomycin-sensitive) A21780 (AS-19), respectively. Sandramycin inhibits cancer cells growth of L1210, B16, HCT118, RPMI8226, A431, RKO, SU-DHL6 and SU-DHL10 cells with IC50 values of 0.02 nM, 0.07 nM, 0.8 nM, 3.8 nM, 3.1 nM, 1.3 nM, 5.9 nM and 3.3 nM, respectively.|In Vivo:|Sandramycin (0.0125-1.6 mg/kg; intraperitoneal injection; daily; for 5 days; CDF1 female mice) treatment shows moderately active in vivo against leukemia P388 in mice.|References:|J A Matson, et al. Sandramycin, a Novel Antitumor Antibiotic Produced by a Nocardioides Sp. Production, Isolation, Characterization and Biological Properties. J Antibiot (Tokyo). 1989 Dec;42(12):1763-7.Katsushi Katayama, et al. Total Synthesis of Sandramycin and Its Analogues via a Multicomponent Assemblage. Org Lett. 2014 Jan 17;16(2):428-31.Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Tyclopyrazoflor

Product Name :
Tyclopyrazoflor

Description:
Tyclopyrazoflor is an anthranilamide compound with pesticidal activity.

CAS:
1477919-27-9

Molecular Weight:
406.85

Formula:
C16H18ClF3N4OS

Chemical Name:
N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfanyl]propanamide

Smiles :
CCN(C(=O)CCSCCC(F)(F)F)C1=CN(N=C1Cl)C1=CN=CC=C1

InChiKey:
DBHVHTPMRCXCIY-UHFFFAOYSA-N

InChi :
InChI=1S/C16H18ClF3N4OS/c1-2-23(14(25)5-8-26-9-6-16(18,19)20)13-11-24(22-15(13)17)12-4-3-7-21-10-12/h3-4,7,10-11H,2,5-6,8-9H2,1H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Neuraminidase} medchemexpress|{Neuraminidase} Cholinesterase (ChE)|{Neuraminidase} Biological Activity|{Neuraminidase} References|{Neuraminidase} custom synthesis|{Neuraminidase} Epigenetic Reader Domain}

Shelf Life:
≥12 months if stored properly.{{MTEP} web|{MTEP} GPCR/G Protein|{MTEP} TGF-beta/Smad|{MTEP} Purity & Documentation|{MTEP} Formula|{MTEP} custom synthesis}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31745963

Additional information:
Tyclopyrazoflor is an anthranilamide compound with pesticidal activity.|Product information|CAS Number: 1477919-27-9|Molecular Weight: 406.85|Formula: C16H18ClF3N4OS|Chemical Name: N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfanyl]propanamide|Smiles: CCN(C(=O)CCSCCC(F)(F)F)C1=CN(N=C1Cl)C1=CN=CC=C1|InChiKey: DBHVHTPMRCXCIY-UHFFFAOYSA-N|InChi: InChI=1S/C16H18ClF3N4OS/c1-2-23(14(25)5-8-26-9-6-16(18,19)20)13-11-24(22-15(13)17)12-4-3-7-21-10-12/h3-4,7,10-11H,2,5-6,8-9H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

2-Maleinimidoethyl mesylate

Product Name :
2-Maleinimidoethyl mesylate

Synonym:
Linker 8

CAS :
155863-36-8

Molecular formula:
C7H9NO5S

Molecular Weight :
219.22

Purity:
≥90% (HPLC)

Specifications:
Purity ≥90% (HPLC)|Appearance Off-white powder|Identity 1H-NMR|PropertiesSolvents chloroform|

{{9041-08-1} web|{9041-08-1} Technical Information|{9041-08-1} Description|{9041-08-1} custom synthesis} {{1334850-99-5} MedChemExpress|{1334850-99-5} Purity & Documentation|{1334850-99-5} Data Sheet|{1334850-99-5} supplier} PMID:31462422 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

DM3

Product Name :
DM3

Description:
DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).

CAS:
796073-54-6

Molecular Weight:
766.34

Formula:
C37H52ClN3O10S

Chemical Name:
(1S, 2R, 3S, 5S, 6S, 20R, 21S)-11-chloro-21-hydroxy-12, 20-dimethoxy-2, 5, 9, 16-tetramethyl-8, 23-dioxo-4, 24-dioxa-9, 22-diazatetracyclo[19.3.1.1, .0, ]hexacosa-10, 12, 14(26), 16, 18-pentaen-6-yl (2S)-2-(N-methyl-4-sulfanylpentanamido)propanoate

Smiles :
C[C@@]12O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@@H](C=CC=C(C)CC1C=C(OC)C(Cl)=C(C=1)N(C)C(=O)C[C@@H]2OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)OC |c:19,t:17|

InChiKey:
LJFFDOBFKICLHN-SVMDFPMXSA-N

InChi :
InChI=1S/C37H52ClN3O10S/c1-20-11-10-12-28(48-9)37(46)19-27(49-35(45)39-37)22(3)33-36(5,51-33)29(50-34(44)23(4)40(6)30(42)14-13-21(2)52)18-31(43)41(7)25-16-24(15-20)17-26(47-8)32(25)38/h10-12,16-17,21-23,27-29,33,46,52H,13-15,18-19H2,1-9H3,(H,39,45)/b12-10-,20-11-/t21?,22-,23+,27+,28-,29+,33+,36+,37+/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).|Product information|CAS Number: 796073-54-6|Molecular Weight: 766.{{Ofatumumab} site|{Ofatumumab} Immunology/Inflammation|{Ofatumumab} Technical Information|{Ofatumumab} In Vivo|{Ofatumumab} custom synthesis|{Ofatumumab} Epigenetic Reader Domain} 34|Formula: C37H52ClN3O10S|Synonym:|Maytansinoid DM3|Chemical Name: (1S, 2R, 3S, 5S, 6S, 20R, 21S)-11-chloro-21-hydroxy-12, 20-dimethoxy-2, 5, 9, 16-tetramethyl-8, 23-dioxo-4, 24-dioxa-9, 22-diazatetracyclo[19.{{Afatinib dimaleate} site|{Afatinib dimaleate} MAPK/ERK Pathway|{Afatinib dimaleate} NF-κB|{Afatinib dimaleate} Biological Activity|{Afatinib dimaleate} Data Sheet|{Afatinib dimaleate} manufacturer} 3.1.1, .0, ]hexacosa-10, 12, 14(26), 16, 18-pentaen-6-yl (2S)-2-(N-methyl-4-sulfanylpentanamido)propanoate|Smiles: C[C@@]12O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@@H](C=CC=C(C)CC1C=C(OC)C(Cl)=C(C=1)N(C)C(=O)C[C@@H]2OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)OC |c:19,t:17||InChiKey: LJFFDOBFKICLHN-SVMDFPMXSA-N|InChi: InChI=1S/C37H52ClN3O10S/c1-20-11-10-12-28(48-9)37(46)19-27(49-35(45)39-37)22(3)33-36(5,51-33)29(50-34(44)23(4)40(6)30(42)14-13-21(2)52)18-31(43)41(7)25-16-24(15-20)17-26(47-8)32(25)38/h10-12,16-17,21-23,27-29,33,46,52H,13-15,18-19H2,1-9H3,(H,39,45)/b12-10-,20-11-/t21?,22-,23+,27+,28-,29+,33+,36+,37+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32491296 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Etobenzanid

Product Name :
Etobenzanid

Synonym:
N-(2,3-Dichlorophenyl)-4-(ethoxymethoxy)benzamide

CAS :
79540-50-4

Molecular formula:
C16H15Cl2NO3

Molecular Weight :
340.2

Purity:
≥98% (HPLC)

Specifications:
Purity ≥98% (HPLC)|Appearance White to off-white powder|Identity 1H-NMR|PropertiesSolvents Soluble in chloroform.{{2001-95-8} MedChemExpress|{2001-95-8} Technical Information|{2001-95-8} Data Sheet|{2001-95-8} supplier} |DownloadsSafety Data Sheet CDX E0065 MSDS.{{508186-14-9} web|{508186-14-9} Technical Information|{508186-14-9} Data Sheet|{508186-14-9} manufacturer} pdf|

PMID:31326215 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Coumarine 343

Product Name :
Coumarine 343

Synonym:
C343, Coumarin 519, 2,3,6,7-Tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizine-10-carboxylic Acid

CAS :
55804-65-4

Molecular formula:
C16H15NO4

Molecular Weight :
285.29

Purity:
≥98% (HPLC)

Specifications:
Purity ≥98% (HPLC)|Appearance Yellow to orange powder|Identity 1H-NMR|PropertiesSolvents Soluble in DMSO or ethanol.{{19545-26-7} MedChemExpress|{19545-26-7} Technical Information|{19545-26-7} In Vivo|{19545-26-7} manufacturer} Slightly soluble in water.{{2173054-79-8} web|{2173054-79-8} Protocol|{2173054-79-8} Formula|{2173054-79-8} supplier} |Melting Point 240 °C (lit.PMID:30000851 )|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

m-PEG2-O-Ph-NH2

Product Name :
m-PEG2-O-Ph-NH2

Description:
m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
65673-48-5

Molecular Weight:
211.26

Formula:
C11H17NO3

Chemical Name:
4-[2-(2-methoxyethoxy)ethoxy]aniline

Smiles :
COCCOCCOC1C=CC(N)=CC=1

InChiKey:
IWXQVPLYQQTJTR-UHFFFAOYSA-N

InChi :
InChI=1S/C11H17NO3/c1-13-6-7-14-8-9-15-11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 65673-48-5|Molecular Weight: 211.26|Formula: C11H17NO3|Chemical Name: 4-[2-(2-methoxyethoxy)ethoxy]aniline|Smiles: COCCOCCOC1C=CC(N)=CC=1|InChiKey: IWXQVPLYQQTJTR-UHFFFAOYSA-N|InChi: InChI=1S/C11H17NO3/c1-13-6-7-14-8-9-15-11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Retifanlimab} web|{Retifanlimab} Purity & Documentation|{Retifanlimab} In stock|{Retifanlimab} supplier|{Retifanlimab} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Colesevelam} medchemexpress|{Colesevelam} Protocol|{Colesevelam} Formula|{Colesevelam} custom synthesis|{Colesevelam} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33357119 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com