[pThr232]Aurora B polyclonal antibody
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[pThr232]Aurora B polyclonal antibody
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Aurora A, B, and C have emerged as key mitotic regulators of mammalian centrosome function, chromosome segregation and cytokinesis. Aurora B is one of several chromosomal passenger proteins involved in chromosome alignment at the metaphase plate and cytokinesis. Phosphorylation of a threonine residue in the Aurora activation loop (Thr232 in human Aurora B) is believed to be an essential regulatory mechanism in Aurora kinase activation. IHC Analysis: Human adrenal tissue stained with [pThr232]Aurora B, pAb at 5µg/ml.{{6090-95-5} site|{6090-95-5} Purity & Documentation|{6090-95-5} Formula|{6090-95-5} custom synthesis} IHC Analysis: Human skin tissue stained with [pThr232]Aurora B, pAb at 5µg/ml. IHC Analysis: Human adrenal tissue stained with [pThr232]Aurora B, pAb at 5µg/ml. IHC Analysis: Human skin tissue stained with [pThr232]Aurora B, pAb at 5µg/ml.
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| Application IHC (PS), WB | Crossreactivity Weakly cross-reacts with mouse, rat, bovine and pig Aurora B. | Formulation Liquid.{{702674-56-4} medchemexpress|{702674-56-4} Technical Information|{702674-56-4} Data Sheet|{702674-56-4} custom synthesis} In PBS, pH 7.PMID:30422571 2, containing 50% glycerol and 0.09% sodium azide. | GenBank ID AAH80581 | Host Rabbit | Immunogen Synthetic peptide corresponding to a portion of human Aurora B phosphorylated at Thr232. | Recommendation Dilutions/Conditions Western Blot (1µg/ml, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. | Source Purified from rabbit serum. | Species Reactivity Human | UniProt ID Q96GD4 | Unit of Measure (UM) µg