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Gardenin B is a flavonoid isolated from Baccharis scandens.{{Troriluzole} MedChemExpress|{Troriluzole} Biological Activity|{Troriluzole} In stock|{Troriluzole} manufacturer|{Troriluzole} Epigenetic Reader Domain} Gardenin B induces cell death in human leukemia cells involves multiple caspases.{{Magrolimab} medchemexpress|{Magrolimab} CD47|{Magrolimab} Protocol|{Magrolimab} Purity|{Magrolimab} supplier|{Magrolimab} Cancer} |Product information|CAS Number: 2798-20-1|Molecular Weight: 358.34|Formula: C19H18O7|Chemical Name: 5-hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one|Smiles: COC1C=CC(=CC=1)C1=CC(=O)C2=C(O)C(OC)=C(OC)C(OC)=C2O1|InChiKey: LXEVSYZNYDZSOB-UHFFFAOYSA-N|InChi: InChI=1S/C19H18O7/c1-22-11-7-5-10(6-8-11)13-9-12(20)14-15(21)17(23-2)19(25-4)18(24-3)16(14)26-13/h5-9,21H,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 16.PMID:24580853 67 mg/mL (46.52 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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TP-238 is a potent and selective dual CECR2/BPTF probe with IC50 values of 30 nM and 350 nM, respectively. TP-238 also inhibits BRD9 with a pIC50 of 5.9 and is less active against other 338 kinases.|Product information|CAS Number: 2415263-04-4|Molecular Weight: 458.58|Formula: C22H30N6O3S|Chemical Name: 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-methanesulfonyl-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine|Smiles: CN(C)CCCOC1C=CC(=CC=1)C1=CC(NCCCN2C=CC=N2)=NC(=N1)S(C)(=O)=O|InChiKey: MSIJJXOWLFOYIN-UHFFFAOYSA-N|InChi: InChI=1S/C22H30N6O3S/c1-27(2)13-6-16-31-19-9-7-18(8-10-19)20-17-21(26-22(25-20)32(3,29)30)23-11-4-14-28-15-5-12-24-28/h5,7-10,12,15,17H,4,6,11,13-14,16H2,1-3H3,(H,23,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{LL-37 amide} web|{LL-37 amide} Bacterial|{LL-37 amide} Epigenetics|{LL-37 amide} Biological Activity|{LL-37 amide} Formula|{LL-37 amide} supplier} |Shelf Life: ≥12 months if stored properly.PMID:28739548 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|TP-238 has on target biochemical activity of 10-30 nM with CECR2 and 100-350 nM with BPTF. TP-238 displays potency for both CECR2 (pIC50 of 7.5) and BPTF (pIC50 of 6.5) in an Alpha screen assay. Isothermal titration calorimetry (ITC) shows TP-238 with a Kd of 10 nM for CECR2 and 120 nM for BPTF.|Products are for research use only. Not for human use.|

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Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity.|Product information|CAS Number: 64316-11-6|Molecular Weight: 236.29|Formula: C2HBr2ClO|Chemical Name: 2,2-dibromo-2-chloroacetaldehyde|Smiles: O=CC(Cl)(Br)Br|InChiKey: SFWAQPWRFZOPKA-UHFFFAOYSA-N|InChi: InChI=1S/C2HBr2ClO/c3-2(4,5)1-6/h1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24202965 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The rank order of haloacetaldehyde (HAL) cytotoxicity is tribromoacetaldehyde (TBAL)≈chloroacetaldehyde (CAL)>dibromoacetaldehyde (DBAL)≈bromochloroacetaldehyde (BCAL)≈ dibromochloroacetaldehyde (DBCAL)>IAL>bromoacetaldehyde (BAL)≈ bromodichloroacetaldehyde (BDCAL)>dichloroacetaldehyde (DCAL)> trichloroacetaldehyde (TCAL). The HALs are highly cytotoxic compared to other DBP chemical classes. The rank order of HAL genotoxicity is DBAL>CAL≈DBCAL>TBAL≈BAL>BDCAL>BCAL≈DCAL>IAL.|Products are for research use only. Not for human use.|

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1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:23341580 |Product information|CAS Number: 1817735-37-7|Molecular Weight: 314.30|Formula: C13H21F3O5|Chemical Name: 1,1,1-trifluoro-3,6,9,12,15-pentaoxaoctadec-17-yne|Smiles: C#CCOCCOCCOCCOCCOCC(F)(F)F|InChiKey: OEQPBBLSVKLHMO-UHFFFAOYSA-N|InChi: InChI=1S/C13H21F3O5/c1-2-3-17-4-5-18-6-7-19-8-9-20-10-11-21-12-13(14,15)16/h1H,3-12H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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Amantanium bromide is a quaternary ammonium compound, which is used as an antiseptic/disinfectant for therapeutic fuction.{{Flecainide} web|{Flecainide} Membrane Transporter/Ion Channel|{Flecainide} Technical Information|{Flecainide} In stock|{Flecainide} custom synthesis|{Flecainide} Autophagy} |Product information|CAS Number: 58158-77-3|Molecular Weight: 472.PMID:32695810 54|Formula: C25H46BrNO2|Chemical Name: [2-(adamantane-1-carbonyloxy)ethyl](decyl)dimethylazanium bromide|Smiles: [Br-].CCCCCCCCCC[N+](C)(C)CCOC(=O)C12CC3CC(C1)CC(C2)C3|InChiKey: VSKHGXKMGTVPPY-UHFFFAOYSA-M|InChi: InChI=1S/C25H46NO2.BrH/c1-4-5-6-7-8-9-10-11-12-26(2,3)13-14-28-24(27)25-18-21-15-22(19-25)17-23(16-21)20-25;/h21-23H,4-20H2,1-3H3;1H/q+1;/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Lenacil is a selective uracil substituted herbicide used for control of both annual grasses, broad leafed weeds and some perennial weeds in sugarcane, apples, alfalfa, peaches, peacans, peppermints (Mentha piperita) and sugar beets.{{Vipivotide tetraxetan} web|{Vipivotide tetraxetan} Drug-Linker Conjugates for ADC|{Vipivotide tetraxetan} Biological Activity|{Vipivotide tetraxetan} Description|{Vipivotide tetraxetan} supplier|{Vipivotide tetraxetan} Autophagy} Lenacil can inhibit photosynthesis.|Product information|CAS Number: 2164-08-1|Molecular Weight: 234.{{Adenosine} site|{Adenosine} Endogenous Metabolite|{Adenosine} Technical Information|{Adenosine} Data Sheet|{Adenosine} manufacturer|{Adenosine} Epigenetic Reader Domain} 29|Formula: C13H18N2O2|Chemical Name: 3-cyclohexyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione|Smiles: O=C1C2CCCC=2NC(=O)N1C1CCCCC1|InChiKey: ZTMKADLOSYKWCA-UHFFFAOYSA-N|InChi: InChI=1S/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:34337881 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.PMID:24324376 |Product information|CAS Number: 1600418-29-8|Molecular Weight: 946.97|Formula: C49H51FN8O11|Chemical Name: 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-{[({[(1S)-1-[({[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0²,¹⁴.0⁴,¹³.0⁶,¹¹.0²⁰,²⁴]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}methyl)carbamoyl]methyl}hexanamide|Smiles: CC1C2CC[C@H](NC(=O)CNC(=O)[C@H](CC3=CC=CC=C3)NC(=O)CNC(=O)CNC(=O)CCCCCN3C(=O)C=CC3=O)C3=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC(=CC=1F)C3=2|InChiKey: XEKFDUNPKACYAY-SODISJPWSA-N|InChi: InChI=1S/C49H51FN8O11/c1-3-49(68)31-19-36-45-29(24-58(36)47(66)30(31)25-69-48(49)67)44-33(14-13-28-26(2)32(50)20-34(56-45)43(28)44)54-40(62)23-53-46(65)35(18-27-10-6-4-7-11-27)55-39(61)22-52-38(60)21-51-37(59)12-8-5-9-17-57-41(63)15-16-42(57)64/h4,6-7,10-11,15-16,19-20,33,35,68H,3,5,8-9,12-14,17-18,21-25H2,1-2H3,(H,51,59)(H,52,60)(H,53,65)(H,54,62)(H,55,61)/t33-,35-,49-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (52.80 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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GS-9901 is a highly selective and orally active PI3Kδ inhibitor, with an IC50 of 1 nM. Has potential to treat rheumatoid arthritis.|Product information|CAS Number: 1640247-87-5|Molecular Weight: 477.88|Formula: C22H17ClFN9O|Chemical Name: 2,4-diamino-6-{[(S)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrile|Smiles: NC1=NC(N)=C(C#N)C(N[C@@H](C2CC2)C2=NC3=C(F)C=CC(Cl)=C3C(=O)N2C2=CN=CC=C2)=N1|InChiKey: XDSXYMOZKDUASY-INIZCTEOSA-N|InChi: InChI=1S/C22H17ClFN9O/c23-13-5-6-14(24)17-15(13)21(34)33(11-2-1-7-28-9-11)20(30-17)16(10-3-4-10)29-19-12(8-25)18(26)31-22(27)32-19/h1-2,5-7,9-10,16H,3-4H2,(H5,26,27,29,31,32)/t16-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|GS-9901 (0.3/1/3 mg/kg, orally, twice daily for 7 days) demonstrates efficacy in a rat model of arthritis and is predicted to be suitable for q.d. dosing in humans.|Products are for research use only. Not for human use.|

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Tiotropium bromide is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).{{Canagliflozin} MedChemExpress|{Canagliflozin} SGLT|{Canagliflozin} Purity & Documentation|{Canagliflozin} Description|{Canagliflozin} custom synthesis|{Canagliflozin} Autophagy} Tiotropium is a muscarinic receptor antagonist, often referred to as an antimuscarinic or anticholinergic agent.{{Grazoprevir} site|{Grazoprevir} Anti-infection|{Grazoprevir} Purity & Documentation|{Grazoprevir} Data Sheet|{Grazoprevir} supplier|{Grazoprevir} Autophagy} Although it does not display selectivity for specific muscarinic receptors, when topically applied it acts mainly on M3 muscarinic receptors[7] located on smooth muscle cells and submucosal glands.PMID:24631563 This leads to a reduction in smooth muscle contraction and mucus secretion and thus produces a bronchodilatory effect.|Product information|CAS Number: 136310-93-5|Molecular Weight: 472.42|Formula: C19H22BrNO4S2|Chemical Name: (1R,2R,4S,5S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0²,⁴]nonan-9-ium bromide|Smiles: [Br-].C[N+]1(C)[C@@H]2CC(C[C@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(C1=CC=CS1)C1=CC=CS1|InChiKey: DQHNAVOVODVIMG-RGECMCKFSA-M|InChi: InChI=1S/C19H22NO4S2.BrH/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15;/h3-8,11-13,16-17,22H,9-10H2,1-2H3;1H/q+1;/p-1/t11?,12-,13+,16-,17+;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures.|Product information|CAS Number: 1001917-37-8|Molecular Weight: 471.PMID:29844565 53|Formula: C25H21N5O3S|Synonym:|MK-8033|MK 8033|MK8033|Chemical Name: 1-[5-(1-methyl-1H-pyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]-N-[(pyridin-2-yl)methyl]methanesulfonamide|Smiles: CN1C=C(C=N1)C1=CC2=C(C=CC3=CC=C(CS(=O)(=O)NCC4=CC=CC=N4)C=C3C2=O)N=C1|InChiKey: VMJFTOSOFDEKTM-UHFFFAOYSA-N|InChi: InChI=1S/C25H21N5O3S/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32,33)29-14-21-4-2-3-9-26-21/h2-13,15,29H,14,16H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|