Additional information:
Chemical dimerizer used in auxin-inducible degron (AID) systems. Induces degradation of a target protein tagged with the auxin-receptor F-box protein Tir1 E3 ligase AID in human colorectral cancer and mouse ES cells or tagged with AFB2 in A431 cells. Endogenous plant hormone.|Product information|CAS Number: 87-51-4|Molecular Weight: 175.18|Formula: C10H9NO2|Synonym:|indolylacetic acid|1H-Indole-3-acetic acid|indoleacetic acid|heteroauxin|IAA|Chemical Name: indole-3-acetic acid|Smiles: OC(=O)CC1=CNC2=CC=CC=C21|InChiKey: SEOVTRFCIGRIMH-UHFFFAOYSA-N|InChi: InChI=1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 35 mg/mL(199.79 mM). Water: undefined.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Eugenol} medchemexpress|{Eugenol} Apoptosis|{Eugenol} Purity & Documentation|{Eugenol} In Vitro|{Eugenol} custom synthesis|{Eugenol} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:36628218 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Indole-3-acetic acid (IAA) induces cytotoxicity in fibroblasts, neutrophils, and several cancer lineages in vitro.|In Vivo:|IAA administration in pregnant rats during days 12-14 might selectively affect the S phase neurons and lead to their apoptosis in the neuroepithelium. It induces microencephaly in rats.|References:|Furukawa S, et al. Toxicol Pathol. 2004, 32(6):659-67.Products are for research use only. Not for human use.|