Archives November 2024

Fmoc-N-methyl-PEG3-CH2CH2COOH

Product Name :
Fmoc-N-methyl-PEG3-CH2CH2COOH

Description:
Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
1807518-77-9

Molecular Weight:
457.52

Formula:
C25H31NO7

Chemical Name:
3-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethoxy]ethoxy}ethoxy)propanoic acid

Smiles :
CN(CCOCCOCCOCCC(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

InChiKey:
JKEBDIJQSKVIID-UHFFFAOYSA-N

InChi :
InChI=1S/C25H31NO7/c1-26(11-13-31-15-17-32-16-14-30-12-10-24(27)28)25(29)33-18-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-9,23H,10-18H2,1H3,(H,27,28)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Coronatine} medchemexpress|{Coronatine} Anti-infection|{Coronatine} Technical Information|{Coronatine} Purity|{Coronatine} custom synthesis|{Coronatine} Epigenetics}

Additional information:
Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1807518-77-9|Molecular Weight: 457.52|Formula: C25H31NO7|Chemical Name: 3-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethoxy]ethoxy}ethoxy)propanoic acid|Smiles: CN(CCOCCOCCOCCC(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: JKEBDIJQSKVIID-UHFFFAOYSA-N|InChi: InChI=1S/C25H31NO7/c1-26(11-13-31-15-17-32-16-14-30-12-10-24(27)28)25(29)33-18-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-9,23H,10-18H2,1H3,(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fmoc-Asn(Trt)-OH} site|{Fmoc-Asn(Trt)-OH} {Biochemical Assay Reagents}|{Fmoc-Asn(Trt)-OH} Biological Activity|{Fmoc-Asn(Trt)-OH} In Vivo|{Fmoc-Asn(Trt)-OH} manufacturer|{Fmoc-Asn(Trt)-OH} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:23756629 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Bis-PEG10-acid

Product Name :
Bis-PEG10-acid

Description:
Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

CAS:
2055023-26-0

Molecular Weight:
558.61

Formula:
C24H46O14

Chemical Name:
4,7,10,13,16,19,22,25,28,31-decaoxatetratriacontanedioic acid

Smiles :
OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

InChiKey:
PPYUGGOOBJIZHK-UHFFFAOYSA-N

InChi :
InChI=1S/C24H46O14/c25-23(26)1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-24(27)28/h1-22H2,(H,25,26)(H,27,28)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Cyclophosphamide} web|{Cyclophosphamide} Cell Cycle/DNA Damage|{Cyclophosphamide} Purity & Documentation|{Cyclophosphamide} Description|{Cyclophosphamide} manufacturer|{Cyclophosphamide} Cancer}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Vinpocetine} medchemexpress|{Vinpocetine} NF-κB|{Vinpocetine} Technical Information|{Vinpocetine} Formula|{Vinpocetine} supplier|{Vinpocetine} Autophagy}

Additional information:
Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 2055023-26-0|Molecular Weight: 558.61|Formula: C24H46O14|Chemical Name: 4,7,10,13,16,19,22,25,28,31-decaoxatetratriacontanedioic acid|Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O|InChiKey: PPYUGGOOBJIZHK-UHFFFAOYSA-N|InChi: InChI=1S/C24H46O14/c25-23(26)1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-24(27)28/h1-22H2,(H,25,26)(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32180353 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com