Proton-pump inhibitor proton-pump.com

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Tyclopyrazoflor is an anthranilamide compound with pesticidal activity.|Product information|CAS Number: 1477919-27-9|Molecular Weight: 406.85|Formula: C16H18ClF3N4OS|Chemical Name: N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfanyl]propanamide|Smiles: CCN(C(=O)CCSCCC(F)(F)F)C1=CN(N=C1Cl)C1=CN=CC=C1|InChiKey: DBHVHTPMRCXCIY-UHFFFAOYSA-N|InChi: InChI=1S/C16H18ClF3N4OS/c1-2-23(14(25)5-8-26-9-6-16(18,19)20)13-11-24(22-15(13)17)12-4-3-7-21-10-12/h3-4,7,10-11H,2,5-6,8-9H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs).|Product information|CAS Number: 796073-54-6|Molecular Weight: 766.{{Ofatumumab} site|{Ofatumumab} Immunology/Inflammation|{Ofatumumab} Technical Information|{Ofatumumab} In Vivo|{Ofatumumab} custom synthesis|{Ofatumumab} Epigenetic Reader Domain} 34|Formula: C37H52ClN3O10S|Synonym:|Maytansinoid DM3|Chemical Name: (1S, 2R, 3S, 5S, 6S, 20R, 21S)-11-chloro-21-hydroxy-12, 20-dimethoxy-2, 5, 9, 16-tetramethyl-8, 23-dioxo-4, 24-dioxa-9, 22-diazatetracyclo[19.{{Afatinib dimaleate} site|{Afatinib dimaleate} MAPK/ERK Pathway|{Afatinib dimaleate} NF-κB|{Afatinib dimaleate} Biological Activity|{Afatinib dimaleate} Data Sheet|{Afatinib dimaleate} manufacturer} 3.1.1, .0, ]hexacosa-10, 12, 14(26), 16, 18-pentaen-6-yl (2S)-2-(N-methyl-4-sulfanylpentanamido)propanoate|Smiles: C[C@@]12O[C@H]1[C@H](C)[C@@H]1C[C@@](O)(NC(=O)O1)[C@@H](C=CC=C(C)CC1C=C(OC)C(Cl)=C(C=1)N(C)C(=O)C[C@@H]2OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)OC |c:19,t:17||InChiKey: LJFFDOBFKICLHN-SVMDFPMXSA-N|InChi: InChI=1S/C37H52ClN3O10S/c1-20-11-10-12-28(48-9)37(46)19-27(49-35(45)39-37)22(3)33-36(5,51-33)29(50-34(44)23(4)40(6)30(42)14-13-21(2)52)18-31(43)41(7)25-16-24(15-20)17-26(47-8)32(25)38/h10-12,16-17,21-23,27-29,33,46,52H,13-15,18-19H2,1-9H3,(H,39,45)/b12-10-,20-11-/t21?,22-,23+,27+,28-,29+,33+,36+,37+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32491296 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).Products are for research use only. Not for human use.|

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m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 65673-48-5|Molecular Weight: 211.26|Formula: C11H17NO3|Chemical Name: 4-[2-(2-methoxyethoxy)ethoxy]aniline|Smiles: COCCOCCOC1C=CC(N)=CC=1|InChiKey: IWXQVPLYQQTJTR-UHFFFAOYSA-N|InChi: InChI=1S/C11H17NO3/c1-13-6-7-14-8-9-15-11-4-2-10(12)3-5-11/h2-5H,6-9,12H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Retifanlimab} web|{Retifanlimab} Purity & Documentation|{Retifanlimab} In stock|{Retifanlimab} supplier|{Retifanlimab} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Colesevelam} medchemexpress|{Colesevelam} Protocol|{Colesevelam} Formula|{Colesevelam} custom synthesis|{Colesevelam} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33357119 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES).{{Hydroxyurea} site|{Hydroxyurea} Cell Cycle/DNA Damage|{Hydroxyurea} Purity & Documentation|{Hydroxyurea} In stock|{Hydroxyurea} custom synthesis|{Hydroxyurea} Cancer} Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.PMID:32658556 |Product information|CAS Number: 53798-97-3|Molecular Weight: 220.18|Formula: C8H12O7|Chemical Name: 3-hydroxy-5-methoxy-3-(methoxycarbonyl)-5-oxopentanoic acid|Smiles: COC(=O)CC(O)(CC(O)=O)C(=O)OC|InChiKey: OMIHCBSQSYMFDP-UHFFFAOYSA-N|InChi: InChI=1S/C8H12O7/c1-14-6(11)4-8(13,3-5(9)10)7(12)15-2/h13H,3-4H2,1-2H3,(H,9,10)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|