Additional information:
Abexinostat, also known as PCI-24781 or CRA-024781, is novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; and the tumor suppressor protein-mediated inhibition of tumor cell division and induction of tumor cell apoptosis.Flunarizine custom synthesis |Product information|CAS Number: 58-33-3|Molecular Weight: 320.PMID:31994151 88|Formula: C17H21ClN2S|Synonym:|Diprazin|Romergan|Lergigan|Phenergan|Fellozine|NSC-231688|Chemical Name: dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine hydrochloride|Smiles: Cl.CN(C)C(C)CN1C2=CC=CC=C2SC2=CC=CC=C12|InChiKey: XXPDBLUZJRXNNZ-UHFFFAOYSA-N|InChi: InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|