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Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Transforming growth factor-beta receptor-associated protein 1; TGF-beta receptor-associated protein 1; TRAP-1; TRAP1; TGFBRAP1 |Host Rabbit |Specificity This TGFBRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human TGFBRAP1. |Species Reactivity Human |Applications WB~~1:1000IHC-P~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Cancer;Signal Transduction |Target |Background Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. |Cellular localization Cytoplasm. Note=Colocalizes with TGF-beta receptors in the absence of signaling |UniProt Q8WUH2 |References |References Rose, J. Phd, et al. Mol. Med. (2010) In press :Le Clerc, S., et al. J. Infect. Dis. 200(8):1194-1201(2009)Hwang, Y., et al. Pharmacogenomics 7(5):697-709(2006)Wurthner, J.U., et al. J. Biol. Chem. 276(22):19495-19502(2001)Provost, P., et al. Proc. Natl. Acad. Sci. U.S.A. 96(5):1881-1885(1999) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

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Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym RING5; RMA1 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:200IF 1:50 – 1:100 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RNF5 (NP_008844.1). |Positive control MCF-7,Jurkat,H460,HepG2,U-251MG,Mouse liver,Mouse spleen,Mouse kidney,Rat brain |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. |Cellular localization Endoplasmic reticulum membrane,Membrane,Mitochondrion membrane,Multi-pass membrane protein |UniProt Q99942 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

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Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Myosin light chain kinase family member 4; Sugen kinase 85; SgK085; MYLK4; SGK085 |Host Rabbit |Specificity This MYLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human MYLK4. |Species Reactivity Human |Applications WB~~1:1000IHC-P~~1:50~100 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Signal Transduction |Target |UniProt Q86YV6 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

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Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym MATA2; MATII; SAMS2 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT2A (NP_005902.1). |Positive control A-549,HeLa,SW620,Mouse lung,Mouse spleen,Rat kidney |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. |UniProt P31153 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.

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Product Details FAQ Citations(0) Video Pictures Documents |Overview |Synonym GCE; GCSP; HYGN1 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:100IF 1:50 – 1:100 |Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 36-290 of human GLDC (NP_000161.2). |Positive control HepG2,DU145 |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). |Cellular localization Mitochondrion |UniProt P23378 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.