Z-AAD-CMK
Product Name :
Z-AAD-CMK
Sequence:
Benzyloxycarbonyl-Ala-Ala-Asp-chloromethylketone
Purity:
≥95% (HPLC)
Molecular Weight:
441.9
Solubility :
Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml) or water (20mg/ml).
Appearance:
White to off-white solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Description:
Caspase inhibitor Irreversible, cell-permeable inhibitor of granzyme B (ID50=0.2068-78-2 Protocol 3 µM).2387633-15-8 MedChemExpress Does not inhibit granzyme A.PMID:25905180 Inhibition of granzyme B with Z-AAD-CMK prevented caspase-3 activation in T cells.
CAS :
Solubility:
Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml) or water (20mg/ml).
Formula:
C19H24ClN3O7
Additional Information :
| Alternative Name Granzyme B inhibitor | Appearance White to off-white solid. | Formula C19H24ClN3O7 | Formulation Lyophilized. | MW 441.9 | Purity ≥95% (HPLC) | Sequence Benzyloxycarbonyl-Ala-Ala-Asp-chloromethylketone | Solubility Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml) or water (20mg/ml). | Source Synthetic.