Additional information:
1-Acetyl-3-o-toluyl-5-fluorouracil is a potent an antineoplastic agent.|Product information|CAS Number: 71861-76-2|Molecular Weight: 290.25|Formula: C14H11FN2O4|Chemical Name: 1-acetyl-5-fluoro-3-(2-methylbenzoyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione|Smiles: CC(=O)N1C=C(F)C(=O)N(C(=O)C2=CC=CC=C2C)C1=O|InChiKey: DRXHAKVGNKHFMB-UHFFFAOYSA-N|InChi: InChI=1S/C14H11FN2O4/c1-8-5-3-4-6-10(8)12(19)17-13(20)11(15)7-16(9(2)18)14(17)21/h3-7H,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{D-Cycloserine} site|{D-Cycloserine} Anti-infection|{D-Cycloserine} Protocol|{D-Cycloserine} In stock|{D-Cycloserine} manufacturer|{D-Cycloserine} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Mirin} MedChemExpress|{Mirin} PI3K/Akt/mTOR|{Mirin} Purity & Documentation|{Mirin} In Vitro|{Mirin} supplier|{Mirin} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31985186 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil demonstrates a remarkable effect on MH134 solid tumors, the effect being more marked than that of subcutaneous administration of 1-Acetyl-3-o-toluyl-5-fluorouracil. Anti-tumor activity of oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at a dose of 0.2 mmol/kg/d is comparable to that of subcutaneous administration of 5-fluorouracil at the same dose. The level of decrease in thymus weight and the magnitude of increase of spleen weight following oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at any dose are smaller than those by subcutaneous administration of 5-fluorouracil (0.2 mmol/kg/d).|Products are for research use only. Not for human use.|