Cyclooctyne-O-PFP ester
Product Name :
Cyclooctyne-O-PFP ester
Description:
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
886209-60-5
Molecular Weight:
348.26
Formula:
C16H13F5O3
Chemical Name:
2,3,4,5,6-pentafluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate
Smiles :
O=C(COC1CCCCCC#C1)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey:
FTKRNGMQMZGSDF-UHFFFAOYSA-N
InChi :
InChI=1S/C16H13F5O3/c17-11-12(18)14(20)16(15(21)13(11)19)24-10(22)8-23-9-6-4-2-1-3-5-7-9/h9H,1-4,6,8H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Congo Red} medchemexpress|{Congo Red} {Fluorescent Dye}|{Congo Red} Protocol|{Congo Red} In stock|{Congo Red} supplier|{Congo Red} Cancer}
Shelf Life:
≥12 months if stored properly.{{Atosiban} web|{Atosiban} Vasopressin Receptor|{Atosiban} TGF-beta/Smad|{Atosiban} Purity & Documentation|{Atosiban} Purity|{Atosiban} custom synthesis}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33203292
Additional information:
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).|Product information|CAS Number: 886209-60-5|Molecular Weight: 348.26|Formula: C16H13F5O3|Chemical Name: 2,3,4,5,6-pentafluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate|Smiles: O=C(COC1CCCCCC#C1)OC1C(F)=C(F)C(F)=C(F)C=1F|InChiKey: FTKRNGMQMZGSDF-UHFFFAOYSA-N|InChi: InChI=1S/C16H13F5O3/c17-11-12(18)14(20)16(15(21)13(11)19)24-10(22)8-23-9-6-4-2-1-3-5-7-9/h9H,1-4,6,8H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (287.14 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|