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Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1807518-77-9|Molecular Weight: 457.52|Formula: C25H31NO7|Chemical Name: 3-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethoxy]ethoxy}ethoxy)propanoic acid|Smiles: CN(CCOCCOCCOCCC(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: JKEBDIJQSKVIID-UHFFFAOYSA-N|InChi: InChI=1S/C25H31NO7/c1-26(11-13-31-15-17-32-16-14-30-12-10-24(27)28)25(29)33-18-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-9,23H,10-18H2,1H3,(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fmoc-Asn(Trt)-OH} site|{Fmoc-Asn(Trt)-OH} {Biochemical Assay Reagents}|{Fmoc-Asn(Trt)-OH} Biological Activity|{Fmoc-Asn(Trt)-OH} In Vivo|{Fmoc-Asn(Trt)-OH} manufacturer|{Fmoc-Asn(Trt)-OH} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:23756629 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 2055023-26-0|Molecular Weight: 558.61|Formula: C24H46O14|Chemical Name: 4,7,10,13,16,19,22,25,28,31-decaoxatetratriacontanedioic acid|Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O|InChiKey: PPYUGGOOBJIZHK-UHFFFAOYSA-N|InChi: InChI=1S/C24H46O14/c25-23(26)1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-24(27)28/h1-22H2,(H,25,26)(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32180353 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:23916866 |Product information|CAS Number: 2093152-84-0|Molecular Weight: 1652.95|Formula: C78H137N7O30|Chemical Name: cyclooct-4-en-1-yl N-{14-[(2-{2-[2-(2-{N-[2-(2-{2-[2-(1-{[(cyclooct-4-en-1-yloxy)carbonyl]amino}-3,6,9,12-tetraoxapentadecan-15-amido)ethoxy]ethoxy}ethoxy)ethyl]-1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12,15,18-hexaoxahenicosan-21-amido}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]-3,6,9,12-tetraoxatetradecan-1-yl}carbamate|Smiles: O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)N(CCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCNC(=O)OC1CCC=CCCC1)CCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCNC(=O)OC1CCC=CCCC1 |c:71,112||InChiKey: LXEACWVJIHRBDM-LEWNYYKSSA-N|InChi: InChI=1S/C78H137N7O30/c86-71(17-26-85-75(90)15-16-76(85)91)79-21-32-97-44-54-109-64-66-113-68-67-112-65-61-106-51-41-96-31-20-74(89)84(27-37-102-47-57-107-52-42-98-33-22-80-72(87)18-29-94-39-49-104-59-62-110-55-45-100-35-24-82-77(92)114-69-11-7-3-1-4-8-12-69)28-38-103-48-58-108-53-43-99-34-23-81-73(88)19-30-95-40-50-105-60-63-111-56-46-101-36-25-83-78(93)115-70-13-9-5-2-6-10-14-70/h1-3,5,15-16,69-70H,4,6-14,17-68H2,(H,79,86)(H,80,87)(H,81,88)(H,82,92)(H,83,93)/b3-1-,5-2-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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Methylamino-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1807521-03-4|Molecular Weight: 203.28|Formula: C10H21NO3|Chemical Name: tert-butyl 3-[2-(methylamino)ethoxy]propanoate|Smiles: CNCCOCCC(=O)OC(C)(C)C|InChiKey: BDFGXPFIPPZYGO-UHFFFAOYSA-N|InChi: InChI=1S/C10H21NO3/c1-10(2,3)14-9(12)5-7-13-8-6-11-4/h11H,5-8H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity.|Product information|CAS Number: 1473404-51-1|Molecular Weight: 402.81|Formula: C16H11ClN6O3S|Chemical Name: 4-[2-(3-chlorophenyl)diazen-1-yl]-3-(4-nitrophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-1-carbothioamide|Smiles: NC(=S)N1NC(=C(N=NC2=CC(Cl)=CC=C2)C1=O)C1C=CC(=CC=1)[N+]([O-])=O|InChiKey: LEQSBTDRMOZWRP-FMQUCBEESA-N|InChi: InChI=1S/C16H11ClN6O3S/c17-10-2-1-3-11(8-10)19-20-14-13(21-22(15(14)24)16(18)27)9-4-6-12(7-5-9)23(25)26/h1-8,21H,(H2,18,27)/b20-19+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 12.5 mg/mL (31.03 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{MDTF} MedChemExpress|{MDTF} Antibody-drug Conjugate/ADC Related|{MDTF} Technical Information|{MDTF} Formula|{MDTF} manufacturer|{MDTF} Autophagy} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Hck-IN-1 (compound B9) shows weak activity against other Src-family members in vitro, with IC50 values >20 μM for c-Src, Lck and Lyn.PMID:25027343 B9 (1 μM; 8 days) completely inhibits Nef-dependent SFK activation at a concentration of 1.0 μM. Hck-IN-1 (0.1, 0.3, 1, 3 μM) also inhibits Nef-mediated enhancement of HIV-1 infectivity in a concentration-dependent manner in the reporter cell line, TZM-bl. Hck-IN-1 inhibits the replication of all eleven HIV-1 Nef chimeras with IC50 values of ~ 300 nM in CEM-T4 cells, demonstrating that the compound is broadly active against HIV replication supported by a wide range of HIV-1 Nef proteins.|Products are for research use only. Not for human use.|

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4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP).{{Streptavidin Protein} MedChemExpress|{Streptavidin Protein} Biological Activity|{Streptavidin Protein} Purity|{Streptavidin Protein} supplier|{Streptavidin Protein} Epigenetics} 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.|Product information|CAS Number: 2138-22-9|Molecular Weight: 144.56|Formula: C6H5ClO2|Chemical Name: 4-chlorobenzene-1,2-diol|Smiles: OC1=CC(Cl)=CC=C1O|InChiKey: WWOBYPKUYODHDG-UHFFFAOYSA-N|InChi: InChI=1S/C6H5ClO2/c7-4-1-2-5(8)6(9)3-4/h1-3,8-9H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (691.PMID:28630660 75 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.|Product information|CAS Number: 1239233-87-4|Molecular Weight: 335.37|Formula: C16H17NO5S|Chemical Name: 2-[3-carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid|Smiles: CC1N=C(SC=1C(O)=O)C1=CC(=C(C=C1)OCC(C)C)C(O)=O|InChiKey: WSCLTDCYZOTAKS-UHFFFAOYSA-N|InChi: InChI=1S/C16H17NO5S/c1-8(2)7-22-12-5-4-10(6-11(12)15(18)19)14-17-9(3)13(23-14)16(20)21/h4-6,8H,7H2,1-3H3,(H,18,19)(H,20,21)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dodecyltrimethylammonium} medchemexpress|{Dodecyltrimethylammonium} {Biochemical Assay Reagents}|{Dodecyltrimethylammonium} Biological Activity|{Dodecyltrimethylammonium} Purity|{Dodecyltrimethylammonium} supplier|{Dodecyltrimethylammonium} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{24(S)-Hydroxycholesterol} medchemexpress|{24(S)-Hydroxycholesterol} Membrane Transporter/Ion Channel|{24(S)-Hydroxycholesterol} Protocol|{24(S)-Hydroxycholesterol} Formula|{24(S)-Hydroxycholesterol} supplier|{24(S)-Hydroxycholesterol} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23577779 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative.|Product information|CAS Number: 19037-69-5|Molecular Weight: 221.17|Formula: C10H7NO5|Chemical Name: 7-hydroxy-4-methyl-8-nitro-2H-chromen-2-one|Smiles: CC1=CC(=O)OC2=C(C(O)=CC=C21)[N+]([O-])=O|InChiKey: BGUBUSIGKOWDPO-UHFFFAOYSA-N|InChi: InChI=1S/C10H7NO5/c1-5-4-8(13)16-10-6(5)2-3-7(12)9(10)11(14)15/h2-4,12H,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Oligomycin} medchemexpress|{Oligomycin} Metabolic Enzyme/Protease|{Oligomycin} Purity & Documentation|{Oligomycin} Description|{Oligomycin} manufacturer|{Oligomycin} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Caspofungin} site|{Caspofungin} Antibiotic|{Caspofungin} Purity & Documentation|{Caspofungin} Description|{Caspofungin} custom synthesis|{Caspofungin} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23991096 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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D-Mannuronic acid sodium, isolated from Macrocystis pyrifera, has the potential in autoimmune encephalomyelitis (EAE), adjuvant induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis studies.{{Benzbromarone} site|{Benzbromarone} Cell Cycle/DNA Damage|{Benzbromarone} Technical Information|{Benzbromarone} Formula|{Benzbromarone} manufacturer|{Benzbromarone} Cancer} |Product information|CAS Number: 921-56-2|Molecular Weight: 216.{{Paeoniflorin} web|{Paeoniflorin} Cell Cycle/DNA Damage|{Paeoniflorin} Technical Information|{Paeoniflorin} Formula|{Paeoniflorin} custom synthesis|{Paeoniflorin} Autophagy} 12|Formula: C6H9NaO7|Chemical Name: sodium (2S,3S,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexanoate|Smiles: [Na+].PMID:23341580 [O-]C(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O|InChiKey: WNFHGZLVUQBPMA-MHFWOIHZSA-M|InChi: InChI=1S/C6H10O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h1-5,8-11H,(H,12,13);/q;+1/p-1/t2-,3-,4+,5+;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 250 mg/mL (1156.76 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.{{Ipilimumab} MedChemExpress|{Ipilimumab} Immunology/Inflammation|{Ipilimumab} Protocol|{Ipilimumab} References|{Ipilimumab} custom synthesis|{Ipilimumab} Epigenetics} This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.Excitation (nm):649, Emission (nm): 670.|Product information|CAS Number: 146368-14-1|Molecular Weight: 753.88|Formula: C37H43N3O10S2|Chemical Name: 1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-2-[5-(1-ethyl-3,3-dimethyl-5-sulfonato-2,3-dihydro-1H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-5-sulfo-3H-indol-1-ium|Smiles: CCN1C(=CC=CC=CC2=[N+](CCCCCC(=O)ON3C(=O)CCC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)C(C)(C)C2=CC(=CC=C12)S([O-])(=O)=O|InChiKey: WXWLHDCCGVWTDZ-UHFFFAOYSA-N|InChi: InChI=1S/C37H43N3O10S2/c1-6-38-29-18-16-25(51(44,45)46)23-27(29)36(2,3)31(38)13-9-7-10-14-32-37(4,5)28-24-26(52(47,48)49)17-19-30(28)39(32)22-12-8-11-15-35(43)50-40-33(41)20-21-34(40)42/h7,9-10,13-14,16-19,23-24H,6,8,11-12,15,20-22H2,1-5H3,(H-,44,45,46,47,48,49)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 25 mg/mL (33.{{SKI II} medchemexpress|{SKI II} Immunology/Inflammation|{SKI II} Biological Activity|{SKI II} Data Sheet|{SKI II} custom synthesis|{SKI II} Epigenetic Reader Domain} 16 mM; Need ultrasonic).PMID:23891445 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|