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3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine.|Product information|CAS Number: 300-48-1|Molecular Weight: 211.21|Formula: C10H13NO4|Chemical Name: (2S)-2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid|Smiles: COC1=CC(C[C@H](N)C(O)=O)=CC=C1O|InChiKey: PFDUUKDQEHURQC-ZETCQYMHSA-N|InChi: InChI=1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)/t7-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 16.{{Ulixertinib} web|{Ulixertinib} Stem Cell/Wnt|{Ulixertinib} Technical Information|{Ulixertinib} References|{Ulixertinib} supplier|{Ulixertinib} Autophagy} 67 mg/mL (78.{{Zandelisib} medchemexpress|{Zandelisib} PI3K/Akt/mTOR|{Zandelisib} Protocol|{Zandelisib} Data Sheet|{Zandelisib} manufacturer|{Zandelisib} Epigenetic Reader Domain} 93 mM; Need ultrasonic).PMID:34645436 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor (KdProduct information|CAS Number: 327613-57-0|Molecular Weight: 817.78|Formula: C38H46Cl2N6O8S|Chemical Name: (2S)-2-{[(2S)-1-(3,5-dichlorobenzenesulfonyl)pyrrolidin-2-yl]formamido}-4-[(2S)-4-methyl-2-[N-methyl-2-(4-{[(2-methylphenyl)carbamoyl]amino}phenyl)acetamido]pentanamido]butanoic acid|Smiles: CN([C@@H](CC(C)C)C(=O)NCC[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)C1C=C(Cl)C=C(Cl)C=1)C(O)=O)C(=O)CC1C=CC(=CC=1)NC(=O)NC1=CC=CC=C1C|InChiKey: MNQBPRHHZPXCKZ-ZDCRTTOTSA-N|InChi: InChI=1S/C38H46Cl2N6O8S/c1-23(2)18-33(45(4)34(47)19-25-11-13-28(14-12-25)42-38(52)44-30-9-6-5-8-24(30)3)35(48)41-16-15-31(37(50)51)43-36(49)32-10-7-17-46(32)55(53,54)29-21-26(39)20-27(40)22-29/h5-6,8-9,11-14,20-23,31-33H,7,10,15-19H2,1-4H3,(H,41,48)(H,43,49)(H,50,51)(H2,42,44,52)/t31-,32-,33-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23613863 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|The combination of BIO5192 (1 mg/kg; i.v.) and Plerixafor (5 mg/kg; s.c.) exert an additive effect on progenitor mobilization. BIO5192 (30 mg/kg; s.c; bid; during days 5 through 14) delays paralysis associated with EAE (experimental autoimmune encephalomyelitis). BIO5192 (1 mg/kg, i.v.) shows the terminal half-life is 1.1 hours. BIO5192 (3, 10, and 30 mg/kg; s.c.) shows half-lives of 1.7, 2.7, and 4.7 hours, respectively. The blood plasma curves show that the AUC for the s.c. route of administration increased about 2.5-fold from 5,460 h*ng/ml for the 3 mg/kg dose to 14,175 h*ng/ml for the 30 mg/kg.|Products are for research use only. Not for human use.|

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Escitalopram is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.|Product information|CAS Number: 128196-01-0|Molecular Weight: 324.39|Formula: C20H21FN2O|Chemical Name: (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile|Smiles: CN(C)CCC[C@]1(OCC2=CC(=CC=C12)C#N)C1C=CC(F)=CC=1|InChiKey: WSEQXVZVJXJVFP-FQEVSTJZSA-N|InChi: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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AM-2394 is a structurally distinct glucokinase activator (GKA). AM-2394 activates glucokinase (GK) with an EC50 of 60 nM.|Product information|CAS Number: 1442684-77-6|Molecular Weight: 423.47|Formula: C22H25N5O4|Chemical Name: 1-[6′-(2-hydroxy-2-methylpropoxy)-4-[(5-methylpyridin-3-yl)oxy]-[3,3′-bipyridin]-6-yl]-3-methylurea|Smiles: CC1C=C(C=NC=1)OC1C=C(NC(=O)NC)N=CC=1C1C=NC(=CC=1)OCC(C)(C)O|InChiKey: QUISANLDBDCMPD-UHFFFAOYSA-N|InChi: InChI=1S/C22H25N5O4/c1-14-7-16(11-24-9-14)31-18-8-19(27-21(28)23-4)25-12-17(18)15-5-6-20(26-10-15)30-13-22(2,3)29/h5-12,29H,13H2,1-4H3,(H2,23,25,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 30 mg/mL (70.84 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:28739548 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|AM-2394, a structurally distinct glucokinase activator that displays a robust reduction in plasma glucose during an oral glucose tolerance test (OGTT) in ob/ob mice at a dose of 3 mg/kg. AM-2394 increases the affinity of glucokinase (GK) for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. AM-2394 exhibits good-to-moderate cross species plasma clearance, volume of distribution, and oral bioavailability, allowing for further evaluation in animal models.|Products are for research use only. Not for human use.|

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Myristicin (Myristicine), a terpene-like active component in Nutmeg which is the seed of Myristica fragrans, is a weak inhibitor of monamine oxidase (MAO) and a mechanism-based inhibitor of CYP1A2.|Product information|CAS Number: 607-91-0|Molecular Weight: 192.21|Formula: C11H12O3|Chemical Name: 4-methoxy-6-(prop-2-en-1-yl)-2H-1, 3-benzodioxole|Smiles: COC1=CC(CC=C)=CC2OCOC1=2|InChiKey: BNWJOHGLIBDBOB-UHFFFAOYSA-N|InChi: InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Trypan Blue (Visionblue, Diphenyl Blue, Direct Blue 14) is a colorimetric dye that stains dead cells with a blue color easily observed using light microscopy at low resolution.|Product information|CAS Number: 72-57-1|Molecular Weight: 960.81|Formula: C34H24N6Na4O14S4|Chemical Name: tetrasodium;5-amino-3-[[4-[4-[(8-amino-1-hydroxy-3, 6-disulfonatonaphthalen-2-yl)diazenyl]-3-methylphenyl]-2-methylphenyl]diazenyl]-4-hydroxynaphthalene-2, 7-disulfonate|Smiles: [Na+].{{Tegoprubart} site|{Tegoprubart} Purity & Documentation|{Tegoprubart} Description|{Tegoprubart} supplier|{Tegoprubart} Epigenetic Reader Domain} [Na+].[Na+].[Na+].CC1C=C(C=CC=1N=NC1=C(C=C2C=C(C=C(N)C2=C1O)S([O-])(=O)=O)S([O-])(=O)=O)C1C=C(C)C(=CC=1)N=NC1=C(C=C2C=C(C=C(N)C2=C1O)S([O-])(=O)=O)S([O-])(=O)=O|InChiKey: GLNADSQYFUSGOU-GPTZEZBUSA-J|InChi: InChI=1S/C34H28N6O14S4.PMID:23618405 4Na/c1-15-7-17(3-5-25(15)37-39-31-27(57(49,50)51)11-19-9-21(55(43,44)45)13-23(35)29(19)33(31)41)18-4-6-26(16(2)8-18)38-40-32-28(58(52,53)54)12-20-10-22(56(46,47)48)14-24(36)30(20)34(32)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C). 100 mg/mL(104.07 mM). 100 mg/mL(104.07 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity.|Product information|CAS Number: 4046-02-0|Molecular Weight: 222.24|Formula: C12H14O4|Chemical Name: ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate|Smiles: COC1=CC(/C=C/C(=O)OCC)=CC=C1O|InChiKey: ATJVZXXHKSYELS-FNORWQNLSA-N|InChi: InChI=1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (449.96 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8.Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58.Products are for research use only. Not for human use.|

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Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.|Product information|CAS Number: 60-12-8|Molecular Weight: 122.{{Quizartinib} site|{Quizartinib} Apoptosis|{Quizartinib} Purity & Documentation|{Quizartinib} In Vitro|{Quizartinib} custom synthesis|{Quizartinib} Cancer} 16|Formula: C8H10O|Synonym:|Phenylethyl alcohol|Phenethyl alcohol|Benzyl carbinol|Chemical Name: 2-phenylethan-1-ol|Smiles: OCCC1C=CC=CC=1|InChiKey: WRMNZCZEMHIOCP-UHFFFAOYSA-N|InChi: InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).{{Doxazosin} web|{Doxazosin} Autophagy|{Doxazosin} Purity & Documentation|{Doxazosin} In stock|{Doxazosin} supplier|{Doxazosin} Epigenetics} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24563649 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Phenethyl alcohol has been shown to interact with the cytoplasmic membrane of other microorganisms in various ways. Escherichia coli phenethyl alcohol, at a concentration higher than that used to induce myxospore formation, inhibits growth by causing a breakdown in the cellular permeabihty barrier. At lower concentrations, phospholipid synthesis, uptake of gentian violet in E. coli and the uptake of several amino acids by Neurospora crassa were all inhibited by phenethyl alcohol.|References:|Lingappa BT, et al. Phenethyl alcohol and tryptophol: autoantibiotics produced by the fungus Candida albicans. Science. 1969 Jan 10;163(3863):192-4.Products are for research use only. Not for human use.|

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Lanraplenib monosuccinate (GS-9876 monosuccinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib monosuccinate (GS-9876 monosuccinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.|Product information|CAS Number: 1800046-97-2|Molecular Weight: 561.59|Formula: C27H31N9O5|Chemical Name: 6-[8-({4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]pyrazin-2-amine; butanedioic acid|Smiles: NC1=CN=CC(=N1)C1=CN2C=CN=C2C(NC2C=CC(=CC=2)N2CCN(CC2)C2COC2)=N1.{{Vobramitamab} medchemexpress|{Vobramitamab} Antibody-drug Conjugate/ADC Related|{Vobramitamab} Technical Information|{Vobramitamab} Purity|{Vobramitamab} custom synthesis|{Vobramitamab} Autophagy} OC(=O)CCC(O)=O|InChiKey: DVFRSTNNWJHWGW-UHFFFAOYSA-N|InChi: InChI=1S/C23H25N9O.{{Isoniazid} web|{Isoniazid} Autophagy|{Isoniazid} Biological Activity|{Isoniazid} References|{Isoniazid} supplier|{Isoniazid} Cancer} C4H6O4/c24-21-12-25-11-19(28-21)20-13-32-6-5-26-23(32)22(29-20)27-16-1-3-17(4-2-16)30-7-9-31(10-8-30)18-14-33-15-18;5-3(6)1-2-4(7)8/h1-6,11-13,18H,7-10,14-15H2,(H2,24,28)(H,27,29);1-2H2,(H,5,6)(H,7,8)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (222.PMID:23522542 58 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Lanraplenib monosuccinate (GS-9876 monosuccinate) inhibits anti-IgM stimulated phosphorylation of AKT, BLNK, BTK, ERK, MEK, and PKCδ in human B cells with EC50 values of 24-51 nM. Lanraplenib monosuccinate inhibits anti-IgM mediated CD69 and CD86 expression on B-cells (EC50=112±10 nM and 164±15 nM, respectively) and anti-IgM /anti-CD40 co-stimulated B cell proliferation (EC50=108±55 nM). In human macrophages, Lanraplenib monosuccinate inhibits IC-stimulated TNFα and IL-1β release (EC50=121±77 nM and 9±17 nM, respectively). Lanraplenib monosuccinate (GS-9876 monosuccinate) inhibits glycoprotein VI (GPVI)-induced phosphorylation of linker for activation of T cells and phospholipase Cγ2, platelet activation and aggregation in human whole blood, and platelet binding to collagen under arterial flow.|Products are for research use only. Not for human use.|

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Pifithrin-alpha is a p53 inactivator.{{Farletuzumab ecteribulin} MedChemExpress|{Farletuzumab ecteribulin} Antibody-drug Conjugate/ADC Related|{Farletuzumab ecteribulin} Technical Information|{Farletuzumab ecteribulin} References|{Farletuzumab ecteribulin} supplier|{Farletuzumab ecteribulin} Autophagy} It also has neuroprotective activity against strokes.PMID:24732841 |Product information|CAS Number: 63208-82-2|Molecular Weight: 367.30|Formula: C16H19BrN2OS|Chemical Name: 2-(2-imino-2,3,4,5,6,7-hexahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethan-1-one hydrobromide|Smiles: Br.CC1C=CC(=CC=1)C(=O)CN1C(=N)SC2CCCCC1=2|InChiKey: HAGVCKULCLQGRF-UHFFFAOYSA-N|InChi: InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|