Additional information:
Sulfo-ara-F-NMN (CZ-48) is a mimetic of nicotinamide mononucleotide (NMN). Sulfo-ara-F-NMN acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). Sulfo-ara-F-NMN induces intracellular cyclic ADP-ribose (cADPR) production.|Product information|CAS Number: 1374663-29-2|Molecular Weight: 352.28|Formula: C11H14FN2O6PS|Chemical Name: 3-carbamoyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-({[hydroxy(oxido)sulfanylidene-λ⁵-phosphanyl]oxy}methyl)oxolan-2-yl]-1λ⁵-pyridin-1-ylium|Smiles: NC(=O)C1C=[N+](C=CC=1)[C@@H]1O[C@H](COP([O-])(O)=S)[C@@H](O)[C@@H]1F|InChiKey: SIQYQBAPGWSZQF-PKIKSRDPSA-N|InChi: InChI=1S/C11H14FN2O6PS/c12-8-9(15)7(5-19-21(17,18)22)20-11(8)14-3-1-2-6(4-14)10(13)16/h1-4,7-9,11,15H,5H2,(H3-,13,16,17,18,22)/t7-,8+,9-,11-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 200 mg/mL (567.{{Nystatin} medchemexpress|{Nystatin} Apoptosis|{Nystatin} Protocol|{Nystatin} In Vitro|{Nystatin} supplier|{Nystatin} Cancer} 73 mM; Need ultrasonic).{{Lansoprazole} web|{Lansoprazole} Membrane Transporter/Ion Channel|{Lansoprazole} Protocol|{Lansoprazole} In Vivo|{Lansoprazole} custom synthesis|{Lansoprazole} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:22664133 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Sterile alpha and Toll/interleukin-1 receptor motif-containing 1 (SARM1) is an adaptor protein in the Toll-like receptor pathway. Sulfo-ara-F-NMN activates SARM1 to produce cyclic ADP-ribose and induces non-apoptotic cell death.|Products are for research use only. Not for human use.|