Fmoc-N-methyl-PEG3-CH2CH2COOH
Product Name :
Fmoc-N-methyl-PEG3-CH2CH2COOH
Description:
Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1807518-77-9
Molecular Weight:
457.52
Formula:
C25H31NO7
Chemical Name:
3-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethoxy]ethoxy}ethoxy)propanoic acid
Smiles :
CN(CCOCCOCCOCCC(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21
InChiKey:
JKEBDIJQSKVIID-UHFFFAOYSA-N
InChi :
InChI=1S/C25H31NO7/c1-26(11-13-31-15-17-32-16-14-30-12-10-24(27)28)25(29)33-18-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-9,23H,10-18H2,1H3,(H,27,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Coronatine} medchemexpress|{Coronatine} Anti-infection|{Coronatine} Technical Information|{Coronatine} Purity|{Coronatine} custom synthesis|{Coronatine} Epigenetics}
Additional information:
Fmoc-N-methyl-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-N-methyl-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1807518-77-9|Molecular Weight: 457.52|Formula: C25H31NO7|Chemical Name: 3-(2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)ethoxy]ethoxy}ethoxy)propanoic acid|Smiles: CN(CCOCCOCCOCCC(O)=O)C(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: JKEBDIJQSKVIID-UHFFFAOYSA-N|InChi: InChI=1S/C25H31NO7/c1-26(11-13-31-15-17-32-16-14-30-12-10-24(27)28)25(29)33-18-23-21-8-4-2-6-19(21)20-7-3-5-9-22(20)23/h2-9,23H,10-18H2,1H3,(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fmoc-Asn(Trt)-OH} site|{Fmoc-Asn(Trt)-OH} {Biochemical Assay Reagents}|{Fmoc-Asn(Trt)-OH} Biological Activity|{Fmoc-Asn(Trt)-OH} In Vivo|{Fmoc-Asn(Trt)-OH} manufacturer|{Fmoc-Asn(Trt)-OH} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:23756629 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|