Nzione trial. Lancet 1999, 354, 44755. Bnaa, K.; Bjerve, K.; Straume, B.; Gram, I.; Thelle, D. Impact of eicosapentaenoic and docosahexaenoic acids on blood stress in hypertension–A population-based intervention trial from the Troms tudy. N. Engl. J. Med. 1990, 322, 79501.Mar. Drugs 2013,18. Mori, T.; Bao, D.; Burke, V.; Puddey, I.; Beilin, L. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood stress and heart rate in humans. Hypertension 1999, 34, 25360. 19. Morris, M.; Sacks, F.; Rosner, B. Does fish oil reduced blood pressure A meta-analysis of controlled trials. Circulation 1993, 88, 52333. 20. De Caterina, R.; Cybulsky, M.; Clinton, S.; Gimbrone, M.; Libby, P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 1994, 14, 1829836. 21. Stulnig, T.M.; Huber, J.; Leitinger, N.; Imre, E.M.; Angelisova, P.; Nowotny, P.; Waldhausl, W. Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition. J. Biol. Chem. 2001, 276, 373357340. 22. Webb, Y.; Hermida-Matsumoto, L.; Resh, M.D. Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids. J. Biol. Chem. 2000, 275, 26170. 23. He, K.; Liu, K.; Daviglus, M.L.; Jenny, N.S.; Mayer-Davis, E.; Jiang, R.; Steffen, L.; Siscovick, D.; Tsai, M.; Herrington, D. Associations of dietary long-chain n-3 polyunsaturated fatty acids and fish with biomarkers of inflammation and endothelial activation (in the Multi-Ethnic Study of Atherosclerosis [MESA]).Sakuranetin Inhibitor Am.Indoxacarb custom synthesis J. Cardiol. 2009, 103, 1238243. 24. Ye, S.; Tan, L.; Ma, J.PMID:23290930 ; Shi, Q.; Li, J. Polyunsaturated docosahexaenoic acid suppresses oxidative pressure induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. Prostaglandins Leukot. Essent. Fatty Acids 2010, 83, 373. 25. Johansen, O.; Seljeflot, I.; Hstmark, A.T.; Arnesen, H. The Effect of supplementation with omega-3 fatty acids on soluble markers of endothelial function in sufferers with coronary heart disease. Arterioscler. Thromb. Vasc. Biol. 1999, 19, 1681686. 26. Seljeflot, I.; Arnesen, H.; Brude, I.R.; Nenseter, M.S.; Drevon, C.A.; Hjermann, I. Effects of omega-3 farry acids and/or antioxidants on endothelial cell markers. Eur. J. Clin. Invest. 1998, 28, 62935. 27. Kanayasu-Toyoda, T.; Morita, I.; Murota, S. Docosapentaenoic acid (22:five, n-3), an elongation metabolite of eicosapentaenoic acid (20:5, n-3), is a potent stimulator of endothelial cell migration on pretreatment in vitro. Prostaglandins Leukot. Essent. Fatty Acids 1996, 54, 31925. 28. McIntosh, A.L.; Huang, H.; Atshaves, B.P.; Wellberg, E.; Kuklev, D.V.; Smith, W.L.; Kier, A.B.; Schroeder, F. Fluorescent n-3 and n-6 quite long chain polyunsaturated fatty acids: Three-photon imaging in living cells expressing liver fatty acid-binding protein. J. Biol. Chem. 2010, 285, 186938708. 29. Salm, P.; Taylor, P.J.; Kostner, K. Simultaneous quantification of total eicosapentaenoic acid, docosahexaenoic acid and arachidonic acid in plasma by high-performance liquid chromatography-tandem mass spectrometry. Biomed. Chromatogr. 2011, 25, 65259. 30. Levy, B.D.; Clish, C.B.; Schmidt, B.; Gronert, K.; Serhan, C.N. Lipid mediator class switching during acute inflammation: signals in resolution. Nat. Immunol. 2001, two, 61219.Mar. Drugs 2013,31. Weyland.