five 5 5 Other people 2b five 5 99b 5 0b 2b 9b 2b 5 99bReaction circumstances: catalyst 00 mg
five five 5 Other people 2b five five 99b five 0b 2b 9b 2b 5 99bReaction circumstances: catalyst 00 mg (noble metal four wt ), CyCONH2 0.25 g (2 mmol), ,2dimethoxyethane 20 g, H2 eight MPa, 43 K, 24 h. Cy cyclohexyl. Representing loss of carbon balance predominantly through KPT-8602 chemical information formation of solid solutions on the catalyst surface. Selectivities in these entries are nominal ones as the low conversions preclude obtained data from being comparable with other entries. Mo PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/16123306 three.7 wt . Table two. Hydrogenation of cyclohexanecarboxamide more than Rh oOxSiO2 catalyst a variety of metal oxidesa.Entry two three 4 5 6 7aMetal oxide CeO2 ZrO2 TiO2 Al2O3 MgO SiO2 l2O3 HZSM5 NoneConv. CyCH2NH2 89 26 24 6 20 27 34 eight 62 two two 53 39 28 7 49 6 5 5 4 4 5 3Selectivity CyCH2OH (CyCH2)2NH 5 five eight 5 four 26 CyCOOH 26 20 Othersb 27 37 40 35 42 53 69Reaction situations: Rh oOxSiO2 00 mg (Rh 4 wt , MoRh ), CyCONH2 0.25 g (two mmol), metal oxide 00 mg, ,2dimethoxyethane 20 g, H2 eight MPa, 43 K, 4 h. Cy cyclohexyl. b Representing loss of carbon balance predominantly by means of formation of solid solutions around the catalyst surface.The catalyst with MoRh 8 shows the highest activity in C hydrogenolysis and amino acid hydrogenation. There may perhaps be difference in the active web sites in between amide hydrogenation and these reactions. We chosen Rh oOxSiO2 (MoRh ) in the following research.three.2. Addition of metal oxides for the catalytic system of RhMoOxSiOWe investigated the effects of addition of metal oxides on the catalysis of Rh oOxSiO2 (MoRh ). The outcomes are shown in table 2. The reaction time was set to become shorter than table to compare the activities. The selectivities of RhMoOxSiO2 were practically precisely the same at various reaction occasions (table , entry ; table two, entry eight). Addition of weakly simple CeO2 and Al2O3 elevated the activity (conversion ofsubstrate) and selectivity to CyCH2NH2. The formation of secondary amine ((CyCH2)2NH) was considerably suppressed by the addition. The addition of CeO2 showed the most effective effect. However, acidic additives which include HZSM5, silicaalumina, ZrO2 and TiO2 showed little effect around the conversion and much decreased the selectivity to CyCH2NH2. Strongly basic MgO also decreased the selectivity to CyCH2NH2 and had small effect around the conversion. The selectivity to `others’, which comprised solid polymerized solutions deposited on the catalyst, was enhanced by addition of acidic or strongly simple oxides. Figure shows the time course of hydrogenation of CyCONH2 over Rh oOxSiO2 in combination with CeO2. The selectivities have been hardly changed until the total conversion of CyCONH2, and after that the selectivity to CyCH2NH2 was progressively decreased and that to (CyCH2)2NH wasSci. Technol. Adv. Mater. six (205)Y Nakagawa et alFigure . Time course of hydrogenation of cyclohexanecarboxamide(CyCONH2) over Rh oOxSiO2 CeO2. Reaction circumstances: RhMoOxSiO2 (Rh 4 wt , MoRh ) 00 mg, CeO2 (uncalcined) 00 mg, ,2dimethoxyethane 20 g, H2 8 MPa, 43 K. Cy cyclohexyl. `Others’ comprise unknown strong merchandise major to loss of carbon balance in the course of catalysis.Figure two. Hydrogenation of cyclohexanecarboxamide (CyCONH2) over Rh oOxSiO2 many amounts of CeO2. Reaction conditions: Rh oOxSiO2 (Rh four wt , MoRh ) 00 mg, CeO2 (uncalcined) 000 mg, ,2dimethoxyethane 20 g, H2 8 MPa, 43 K, four h. Cy cyclohexyl. `Others’ comprise unknown solid merchandise top to loss of carbon balance through catalysis.steadily enhanced. The highest yield of CyCH2NH2 was 63 obtained at eight h (equation (three)). Although the yield value was reduced tha.