Clinical trial, explored the use of different structured formats to communicate IRE1 Inhibitor III supplier information about food PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20688899 irradiation [22]. Women (N = 195) were presented with one of eight documents that explained and diagrammed the food irradiation process. The sample was restricted to women as they were deemed to be the major purchaser of household food. Some brochures used technical language and others contained non-technical language.One half of the sample was also given a detailed verbal presentation of the major arguments for and against food irradiation, and the other half was given a short history of the use of irradiated food. The outcomes of this study indicate that the use of technical language, non-technical language or information about the pros/ cons of food irradiation had little impact on the respondents’ judgment. Acceptance increased when respondents knew the history of prestigious people (e.g., astronauts) who used the process and that a number of reputable federal and international agencies approved of irradiation. Overall, people who were well-informed about the topic had higher levels of acceptance. Those who scored high in knowledge of food irradiation also had higher levels of education (Pearson’s r = .0.26), less distrust (r = -.28), lower alienation (r = -.20), anti-tech scores (r = -.23) and less fear of radiation (r = -.21). A key finding was that trust greatly impacted acceptability. Trust was related to industry in general, the food irradiation business specifically, government regulatory industries and the science that says food irradiation is safe. Burger et al.’s controlled clinical trial examined the efficacy of two different formats for communicating the risks of eating contaminated fish: a brochure and a classroom presentation [23]. The sample included pregnant women and other women of childbearing age (N = 96) in the Newark Bay area of New Jersey. The information presented in both formats was the same, but the classroom lesson was longer and each point was presented in more detail than in the brochure. Both formats used detailed diagrams and each was available in English or Spanish. Ninety-six percent of the women who heard the presentation understood the information, compared with 72 of those reading the brochure. Those who heard the lesson provided the correct answers more often than did those who read the same information in the brochure for 18 of the 20 questions asked (p < .001). A randomized 2 ?2 post-test design was used in the Netherlands by Gutteling to examine the effectiveness of brochures outlining the risks and benefits of a new hazardous technology [a plant for the oxygen-free burning of polyvinyl chloride (PVC)] [13]. Participants in the intervention group (N = 383) received one of two brochures, whereas the control group (N = 125) did not receive a brochure. The brochures were "sourced" from the government and a private company. Both brochures contained identical information with the exception of the conclusions. One half of the brochures contained explicit conclusions about the risks and benefits, and the other half did not have explicit conclusions. The brochure with the explicit conclusions also contained 12 evaluative remarks within the overall text that were notFitzpatrick-Lewis et al. Environmental Health 2010, 9:67 http://www.ehjournal.net/content/9/1/Page 7 ofpresent in the other version of the brochure. The groups receiving the information, regardless of source, showed a statistically signific.