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Featured Uncategorized

Methylamino-PEG1-Boc

by Proton-pump inhibitor Oct 30, 2024

Product Name :
Methylamino-PEG1-Boc

Description:
Methylamino-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
1807521-03-4

Molecular Weight:
203.28

Formula:
C10H21NO3

Chemical Name:
tert-butyl 3-[2-(methylamino)ethoxy]propanoate

Smiles :
CNCCOCCC(=O)OC(C)(C)C

InChiKey:
BDFGXPFIPPZYGO-UHFFFAOYSA-N

InChi :
InChI=1S/C10H21NO3/c1-10(2,3)14-9(12)5-7-13-8-6-11-4/h11H,5-8H2,1-4H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Zanubrutinib} web|{Zanubrutinib} Protein Tyrosine Kinase/RTK|{Zanubrutinib} Biological Activity|{Zanubrutinib} References|{Zanubrutinib} custom synthesis|{Zanubrutinib} Autophagy}

Shelf Life:
≥12 months if stored properly.{{Lornoxicam} site|{Lornoxicam} TNF Receptor|{Lornoxicam} Protocol|{Lornoxicam} References|{Lornoxicam} custom synthesis|{Lornoxicam} Autophagy}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:36014399

Additional information:
Methylamino-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1807521-03-4|Molecular Weight: 203.28|Formula: C10H21NO3|Chemical Name: tert-butyl 3-[2-(methylamino)ethoxy]propanoate|Smiles: CNCCOCCC(=O)OC(C)(C)C|InChiKey: BDFGXPFIPPZYGO-UHFFFAOYSA-N|InChi: InChI=1S/C10H21NO3/c1-10(2,3)14-9(12)5-7-13-8-6-11-4/h11H,5-8H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Featured Uncategorized

Hck-IN-1

by Proton-pump inhibitor Oct 29, 2024

Product Name :
Hck-IN-1

Description:
Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity.

CAS:
1473404-51-1

Molecular Weight:
402.81

Formula:
C16H11ClN6O3S

Chemical Name:
4-[2-(3-chlorophenyl)diazen-1-yl]-3-(4-nitrophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-1-carbothioamide

Smiles :
NC(=S)N1NC(=C(N=NC2=CC(Cl)=CC=C2)C1=O)C1C=CC(=CC=1)[N+]([O-])=O

InChiKey:
LEQSBTDRMOZWRP-FMQUCBEESA-N

InChi :
InChI=1S/C16H11ClN6O3S/c17-10-2-1-3-11(8-10)19-20-14-13(21-22(15(14)24)16(18)27)9-4-6-12(7-5-9)23(25)26/h1-8,21H,(H2,18,27)/b20-19+

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.{{Perindopril} web|{Perindopril} Stem Cell/Wnt|{Perindopril} Biological Activity|{Perindopril} Formula|{Perindopril} custom synthesis|{Perindopril} Autophagy}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 μM, >20 μM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity.|Product information|CAS Number: 1473404-51-1|Molecular Weight: 402.81|Formula: C16H11ClN6O3S|Chemical Name: 4-[2-(3-chlorophenyl)diazen-1-yl]-3-(4-nitrophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-1-carbothioamide|Smiles: NC(=S)N1NC(=C(N=NC2=CC(Cl)=CC=C2)C1=O)C1C=CC(=CC=1)[N+]([O-])=O|InChiKey: LEQSBTDRMOZWRP-FMQUCBEESA-N|InChi: InChI=1S/C16H11ClN6O3S/c17-10-2-1-3-11(8-10)19-20-14-13(21-22(15(14)24)16(18)27)9-4-6-12(7-5-9)23(25)26/h1-8,21H,(H2,18,27)/b20-19+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 12.5 mg/mL (31.03 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{MDTF} MedChemExpress|{MDTF} Antibody-drug Conjugate/ADC Related|{MDTF} Technical Information|{MDTF} Formula|{MDTF} manufacturer|{MDTF} Autophagy} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Hck-IN-1 (compound B9) shows weak activity against other Src-family members in vitro, with IC50 values >20 μM for c-Src, Lck and Lyn.PMID:25027343 B9 (1 μM; 8 days) completely inhibits Nef-dependent SFK activation at a concentration of 1.0 μM. Hck-IN-1 (0.1, 0.3, 1, 3 μM) also inhibits Nef-mediated enhancement of HIV-1 infectivity in a concentration-dependent manner in the reporter cell line, TZM-bl. Hck-IN-1 inhibits the replication of all eleven HIV-1 Nef chimeras with IC50 values of ~ 300 nM in CEM-T4 cells, demonstrating that the compound is broadly active against HIV replication supported by a wide range of HIV-1 Nef proteins.|Products are for research use only. Not for human use.|

Featured Uncategorized

4-Chlorocatechol

by Proton-pump inhibitor Oct 28, 2024

Product Name :
4-Chlorocatechol

Description:
4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.

CAS:
2138-22-9

Molecular Weight:
144.56

Formula:
C6H5ClO2

Chemical Name:
4-chlorobenzene-1,2-diol

Smiles :
OC1=CC(Cl)=CC=C1O

InChiKey:
WWOBYPKUYODHDG-UHFFFAOYSA-N

InChi :
InChI=1S/C6H5ClO2/c7-4-1-2-5(8)6(9)3-4/h1-3,8-9H

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{SC209} web|{SC209} JAK/STAT Signaling|{SC209} Protocol|{SC209} Description|{SC209} supplier|{SC209} Epigenetics}

Additional information:
4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP).{{Streptavidin Protein} MedChemExpress|{Streptavidin Protein} Biological Activity|{Streptavidin Protein} Purity|{Streptavidin Protein} supplier|{Streptavidin Protein} Epigenetics} 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.|Product information|CAS Number: 2138-22-9|Molecular Weight: 144.56|Formula: C6H5ClO2|Chemical Name: 4-chlorobenzene-1,2-diol|Smiles: OC1=CC(Cl)=CC=C1O|InChiKey: WWOBYPKUYODHDG-UHFFFAOYSA-N|InChi: InChI=1S/C6H5ClO2/c7-4-1-2-5(8)6(9)3-4/h1-3,8-9H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (691.PMID:28630660 75 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

Febuxostat dicarboxylic acid impurity

by Proton-pump inhibitor Oct 27, 2024

Product Name :
Febuxostat dicarboxylic acid impurity

Description:
Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.

CAS:
1239233-87-4

Molecular Weight:
335.37

Formula:
C16H17NO5S

Chemical Name:
2-[3-carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

Smiles :
CC1N=C(SC=1C(O)=O)C1=CC(=C(C=C1)OCC(C)C)C(O)=O

InChiKey:
WSCLTDCYZOTAKS-UHFFFAOYSA-N

InChi :
InChI=1S/C16H17NO5S/c1-8(2)7-22-12-5-4-10(6-11(12)15(18)19)14-17-9(3)13(23-14)16(20)21/h4-6,8H,7H2,1-3H3,(H,18,19)(H,20,21)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.|Product information|CAS Number: 1239233-87-4|Molecular Weight: 335.37|Formula: C16H17NO5S|Chemical Name: 2-[3-carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid|Smiles: CC1N=C(SC=1C(O)=O)C1=CC(=C(C=C1)OCC(C)C)C(O)=O|InChiKey: WSCLTDCYZOTAKS-UHFFFAOYSA-N|InChi: InChI=1S/C16H17NO5S/c1-8(2)7-22-12-5-4-10(6-11(12)15(18)19)14-17-9(3)13(23-14)16(20)21/h4-6,8H,7H2,1-3H3,(H,18,19)(H,20,21)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dodecyltrimethylammonium} medchemexpress|{Dodecyltrimethylammonium} {Biochemical Assay Reagents}|{Dodecyltrimethylammonium} Biological Activity|{Dodecyltrimethylammonium} Purity|{Dodecyltrimethylammonium} supplier|{Dodecyltrimethylammonium} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{24(S)-Hydroxycholesterol} medchemexpress|{24(S)-Hydroxycholesterol} Membrane Transporter/Ion Channel|{24(S)-Hydroxycholesterol} Protocol|{24(S)-Hydroxycholesterol} Formula|{24(S)-Hydroxycholesterol} supplier|{24(S)-Hydroxycholesterol} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23577779 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

7-Hydroxy-4-methyl-8-nitrocoumarin

by Proton-pump inhibitor Oct 27, 2024

Product Name :
7-Hydroxy-4-methyl-8-nitrocoumarin

Description:
7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative.

CAS:
19037-69-5

Molecular Weight:
221.17

Formula:
C10H7NO5

Chemical Name:
7-hydroxy-4-methyl-8-nitro-2H-chromen-2-one

Smiles :
CC1=CC(=O)OC2=C(C(O)=CC=C21)[N+]([O-])=O

InChiKey:
BGUBUSIGKOWDPO-UHFFFAOYSA-N

InChi :
InChI=1S/C10H7NO5/c1-5-4-8(13)16-10-6(5)2-3-7(12)9(10)11(14)15/h2-4,12H,1H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative.|Product information|CAS Number: 19037-69-5|Molecular Weight: 221.17|Formula: C10H7NO5|Chemical Name: 7-hydroxy-4-methyl-8-nitro-2H-chromen-2-one|Smiles: CC1=CC(=O)OC2=C(C(O)=CC=C21)[N+]([O-])=O|InChiKey: BGUBUSIGKOWDPO-UHFFFAOYSA-N|InChi: InChI=1S/C10H7NO5/c1-5-4-8(13)16-10-6(5)2-3-7(12)9(10)11(14)15/h2-4,12H,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Oligomycin} medchemexpress|{Oligomycin} Metabolic Enzyme/Protease|{Oligomycin} Purity & Documentation|{Oligomycin} Description|{Oligomycin} manufacturer|{Oligomycin} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Caspofungin} site|{Caspofungin} Antibiotic|{Caspofungin} Purity & Documentation|{Caspofungin} Description|{Caspofungin} custom synthesis|{Caspofungin} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23991096 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

D-Mannuronic acid sodium

by Proton-pump inhibitor Oct 26, 2024

Product Name :
D-Mannuronic acid sodium

Description:
D-Mannuronic acid sodium, isolated from Macrocystis pyrifera, has the potential in autoimmune encephalomyelitis (EAE), adjuvant induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis studies.

CAS:
921-56-2

Molecular Weight:
216.12

Formula:
C6H9NaO7

Chemical Name:
sodium (2S,3S,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexanoate

Smiles :
[Na+].[O-]C(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O

InChiKey:
WNFHGZLVUQBPMA-MHFWOIHZSA-M

InChi :
InChI=1S/C6H10O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h1-5,8-11H,(H,12,13);/q;+1/p-1/t2-,3-,4+,5+;/m1./s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
D-Mannuronic acid sodium, isolated from Macrocystis pyrifera, has the potential in autoimmune encephalomyelitis (EAE), adjuvant induced arthritis (AIA), nephrotic syndrome, and acute glomerulonephritis studies.{{Benzbromarone} site|{Benzbromarone} Cell Cycle/DNA Damage|{Benzbromarone} Technical Information|{Benzbromarone} Formula|{Benzbromarone} manufacturer|{Benzbromarone} Cancer} |Product information|CAS Number: 921-56-2|Molecular Weight: 216.{{Paeoniflorin} web|{Paeoniflorin} Cell Cycle/DNA Damage|{Paeoniflorin} Technical Information|{Paeoniflorin} Formula|{Paeoniflorin} custom synthesis|{Paeoniflorin} Autophagy} 12|Formula: C6H9NaO7|Chemical Name: sodium (2S,3S,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexanoate|Smiles: [Na+].PMID:23341580 [O-]C(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O|InChiKey: WNFHGZLVUQBPMA-MHFWOIHZSA-M|InChi: InChI=1S/C6H10O7.Na/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h1-5,8-11H,(H,12,13);/q;+1/p-1/t2-,3-,4+,5+;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : 250 mg/mL (1156.76 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

CY5-SE

by Proton-pump inhibitor Oct 25, 2024

Product Name :
CY5-SE

Description:
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.Excitation (nm):649, Emission (nm): 670.

CAS:
146368-14-1

Molecular Weight:
753.88

Formula:
C37H43N3O10S2

Chemical Name:
1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-2-[5-(1-ethyl-3,3-dimethyl-5-sulfonato-2,3-dihydro-1H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-5-sulfo-3H-indol-1-ium

Smiles :
CCN1C(=CC=CC=CC2=[N+](CCCCCC(=O)ON3C(=O)CCC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)C(C)(C)C2=CC(=CC=C12)S([O-])(=O)=O

InChiKey:
WXWLHDCCGVWTDZ-UHFFFAOYSA-N

InChi :
InChI=1S/C37H43N3O10S2/c1-6-38-29-18-16-25(51(44,45)46)23-27(29)36(2,3)31(38)13-9-7-10-14-32-37(4,5)28-24-26(52(47,48)49)17-19-30(28)39(32)22-12-8-11-15-35(43)50-40-33(41)20-21-34(40)42/h7,9-10,13-14,16-19,23-24H,6,8,11-12,15,20-22H2,1-5H3,(H-,44,45,46,47,48,49)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.{{Ipilimumab} MedChemExpress|{Ipilimumab} Immunology/Inflammation|{Ipilimumab} Protocol|{Ipilimumab} References|{Ipilimumab} custom synthesis|{Ipilimumab} Epigenetics} This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.Excitation (nm):649, Emission (nm): 670.|Product information|CAS Number: 146368-14-1|Molecular Weight: 753.88|Formula: C37H43N3O10S2|Chemical Name: 1-{6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}-2-[5-(1-ethyl-3,3-dimethyl-5-sulfonato-2,3-dihydro-1H-indol-2-ylidene)penta-1,3-dien-1-yl]-3,3-dimethyl-5-sulfo-3H-indol-1-ium|Smiles: CCN1C(=CC=CC=CC2=[N+](CCCCCC(=O)ON3C(=O)CCC3=O)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)C(C)(C)C2=CC(=CC=C12)S([O-])(=O)=O|InChiKey: WXWLHDCCGVWTDZ-UHFFFAOYSA-N|InChi: InChI=1S/C37H43N3O10S2/c1-6-38-29-18-16-25(51(44,45)46)23-27(29)36(2,3)31(38)13-9-7-10-14-32-37(4,5)28-24-26(52(47,48)49)17-19-30(28)39(32)22-12-8-11-15-35(43)50-40-33(41)20-21-34(40)42/h7,9-10,13-14,16-19,23-24H,6,8,11-12,15,20-22H2,1-5H3,(H-,44,45,46,47,48,49)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 25 mg/mL (33.{{SKI II} medchemexpress|{SKI II} Immunology/Inflammation|{SKI II} Biological Activity|{SKI II} Data Sheet|{SKI II} custom synthesis|{SKI II} Epigenetic Reader Domain} 16 mM; Need ultrasonic).PMID:23891445 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

N-Benzyl-N-bis-PEG2

by Proton-pump inhibitor Oct 24, 2024

Product Name :
N-Benzyl-N-bis-PEG2

Description:
N-Benzyl-N-bis-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
119580-47-1

Molecular Weight:
283.36

Formula:
C15H25NO4

Chemical Name:
2-(2-{benzyl[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol

Smiles :
OCCOCCN(CC1C=CC=CC=1)CCOCCO

InChiKey:
HBHHHXUOMCTWCK-UHFFFAOYSA-N

InChi :
InChI=1S/C15H25NO4/c17-8-12-19-10-6-16(7-11-20-13-9-18)14-15-4-2-1-3-5-15/h1-5,17-18H,6-14H2

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{PS10} medchemexpress|{PS10} Metabolic Enzyme/Protease|{PS10} Protocol|{PS10} In stock|{PS10} supplier|{PS10} Autophagy}

Additional information:
N-Benzyl-N-bis-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Idarubicin} web|{Idarubicin} Cell Cycle/DNA Damage|{Idarubicin} Protocol|{Idarubicin} References|{Idarubicin} custom synthesis|{Idarubicin} Epigenetic Reader Domain} |Product information|CAS Number: 119580-47-1|Molecular Weight: 283.36|Formula: C15H25NO4|Chemical Name: 2-(2-{benzyl[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol|Smiles: OCCOCCN(CC1C=CC=CC=1)CCOCCO|InChiKey: HBHHHXUOMCTWCK-UHFFFAOYSA-N|InChi: InChI=1S/C15H25NO4/c17-8-12-19-10-6-16(7-11-20-13-9-18)14-15-4-2-1-3-5-15/h1-5,17-18H,6-14H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25558565 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

Featured Uncategorized

NH2-Ph-C4-acid-NH2-Me

by Proton-pump inhibitor Oct 23, 2024

Product Name :
NH2-Ph-C4-acid-NH2-Me

Description:
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs.

CAS:
1263819-48-2

Molecular Weight:
222.28

Formula:
C12H18N2O2

Chemical Name:
(2S,4R)-4-amino-5-(4-aminophenyl)-2-methylpentanoic acid

Smiles :
C[C@@H](C[C@@H](N)CC1C=CC(N)=CC=1)C(O)=O

InChiKey:
JPGXUEFAQWNCEO-GZMMTYOYSA-N

InChi :
InChI=1S/C12H18N2O2/c1-8(12(15)16)6-11(14)7-9-2-4-10(13)5-3-9/h2-5,8,11H,6-7,13-14H2,1H3,(H,15,16)/t8-,11+/m0/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 1263819-48-2|Molecular Weight: 222.28|Formula: C12H18N2O2|Chemical Name: (2S,4R)-4-amino-5-(4-aminophenyl)-2-methylpentanoic acid|Smiles: C[C@@H](C[C@@H](N)CC1C=CC(N)=CC=1)C(O)=O|InChiKey: JPGXUEFAQWNCEO-GZMMTYOYSA-N|InChi: InChI=1S/C12H18N2O2/c1-8(12(15)16)6-11(14)7-9-2-4-10(13)5-3-9/h2-5,8,11H,6-7,13-14H2,1H3,(H,15,16)/t8-,11+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Linagliptin} site|{Linagliptin} Ferroptosis|{Linagliptin} Technical Information|{Linagliptin} References|{Linagliptin} manufacturer|{Linagliptin} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Tacrolimus} web|{Tacrolimus} FKBP|{Tacrolimus} Purity & Documentation|{Tacrolimus} Purity|{Tacrolimus} manufacturer|{Tacrolimus} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:25040798 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

Featured Uncategorized

Fibrin

by Proton-pump inhibitor Oct 23, 2024

Product Name :
Fibrin

Description:
Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation.

CAS:
9001-31-4

Molecular Weight:
145.16

Formula:
C5H11N3O2

Chemical Name:
2-amino-N-[(methylcarbamoyl)methyl]acetamide

Smiles :
CNC(=O)CNC(=O)CN

InChiKey:
BWGVNKXGVNDBDI-UHFFFAOYSA-N

InChi :
InChI=1S/C5H11N3O2/c1-7-5(10)3-8-4(9)2-6/h2-3,6H2,1H3,(H,7,10)(H,8,9)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Penicillin V} web|{Penicillin V} Antibiotic|{Penicillin V} Protocol|{Penicillin V} In stock|{Penicillin V} custom synthesis|{Penicillin V} Autophagy}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding.{{Anti-Mouse IL-1b Antibody} web|{Anti-Mouse IL-1b Antibody} Interleukin Related|{Anti-Mouse IL-1b Antibody} Protocol|{Anti-Mouse IL-1b Antibody} References|{Anti-Mouse IL-1b Antibody} custom synthesis|{Anti-Mouse IL-1b Antibody} Epigenetics} Fibrin is the major component of the blood clot and is used for coagulation.PMID:25429455 |Product information|CAS Number: 9001-31-4|Molecular Weight: 145.16|Formula: C5H11N3O2|Chemical Name: 2-amino-N-[(methylcarbamoyl)methyl]acetamide|Smiles: CNC(=O)CNC(=O)CN|InChiKey: BWGVNKXGVNDBDI-UHFFFAOYSA-N|InChi: InChI=1S/C5H11N3O2/c1-7-5(10)3-8-4(9)2-6/h2-3,6H2,1H3,(H,7,10)(H,8,9)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

2, 3-Butanedione-2-monoxime

by Proton-pump inhibitor Oct 22, 2024

Product Name :
2, 3-Butanedione-2-monoxime

Description:
2,3-Butanedione-2-monoxime is a myosin ATPase inhibitor. Myosin, an ATPase, can convert chemical energy into directed movement and is regarded as a molecular motor. Myosin has various shapes and sizes. More than 11 myosin classes have been identified, and more will be found. The common feature of all of these molecules is a section close to the N terminus, which can be identified as a motor domain. In vitro: 2,3-Butanedione-2-monoxime (BDM), a general probe of myosin function, was widely used in muscle research as a low-affinity but specific chemical phosphatase that could reversibly inhibit the myosin cross-bridge cycle. It was found that wild-type cells treated with BDM at 20 mM for around two generation times were smaller than untreated controls and showed a septation index about twice that observed in the absence of the inhibitor. Moreover, the organization of actin at the cell poles was disorganized in the presence of BDM, however, cells formed a cytokinetic actin ring. In addition, when nitrogen-starved stationary-phase cells were reinoculated into fresh medium in the presence of BDM, the time taken to repolarize the actin cytoskeleton and to resume the characteristic vegetative cell shape were both delayed substantially . In vivo: So far, there is no animal in vivo data reported. Clinical trial: So far, no clinical study has been conducted.

CAS:
57-71-6

Molecular Weight:
101.10

Formula:
C4H7NO2

Chemical Name:
(3E)-3-(hydroxyimino)butan-2-one

Smiles :
C/C(=N\O)/C(C)=O

InChiKey:
FSEUPUDHEBLWJY-HWKANZROSA-N

InChi :
InChI=1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
2,3-Butanedione-2-monoxime is a myosin ATPase inhibitor. Myosin, an ATPase, can convert chemical energy into directed movement and is regarded as a molecular motor. Myosin has various shapes and sizes. More than 11 myosin classes have been identified, and more will be found. The common feature of all of these molecules is a section close to the N terminus, which can be identified as a motor domain. In vitro: 2,3-Butanedione-2-monoxime (BDM), a general probe of myosin function, was widely used in muscle research as a low-affinity but specific chemical phosphatase that could reversibly inhibit the myosin cross-bridge cycle. It was found that wild-type cells treated with BDM at 20 mM for around two generation times were smaller than untreated controls and showed a septation index about twice that observed in the absence of the inhibitor.{{Olanzapine} MedChemExpress|{Olanzapine} Autophagy|{Olanzapine} Purity & Documentation|{Olanzapine} Data Sheet|{Olanzapine} supplier|{Olanzapine} Epigenetics} Moreover, the organization of actin at the cell poles was disorganized in the presence of BDM, however, cells formed a cytokinetic actin ring.{{Treosulfan} site|{Treosulfan} DNA Alkylator/Crosslinker|{Treosulfan} Technical Information|{Treosulfan} Purity|{Treosulfan} manufacturer|{Treosulfan} Epigenetics} In addition, when nitrogen-starved stationary-phase cells were reinoculated into fresh medium in the presence of BDM, the time taken to repolarize the actin cytoskeleton and to resume the characteristic vegetative cell shape were both delayed substantially .PMID:23290930 In vivo: So far, there is no animal in vivo data reported. Clinical trial: So far, no clinical study has been conducted.|Product information|CAS Number: 57-71-6|Molecular Weight: 101.10|Formula: C4H7NO2|Chemical Name: (3E)-3-(hydroxyimino)butan-2-one|Smiles: C/C(=N\O)/C(C)=O|InChiKey: FSEUPUDHEBLWJY-HWKANZROSA-N|InChi: InChI=1S/C4H7NO2/c1-3(5-7)4(2)6/h7H,1-2H3/b5-3+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

Inosine-5′-monophosphate (sodium salt hydrate)

by Proton-pump inhibitor Oct 21, 2024

Product Name :
Inosine-5′-monophosphate (sodium salt hydrate)

Description:
Product information

CAS:
20813-76-7

Molecular Weight:
536.29

Formula:
C10H27N4Na2O16P

Chemical Name:
disodium octahydrate [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl phosphate

Smiles :
O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]P([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CNC2=O

InChiKey:
QKWLBOYKTJDMLH-NAGQJCCQSA-L

InChi :
InChI=1S/C10H13N4O8P.2Na.8H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;;;;;;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;8*1H2/q;2*+1;;;;;;;;/p-2/t4-,6-,7-,10-;;;;;;;;;;/m1………./s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Product information|CAS Number: 20813-76-7|Molecular Weight: 536.{{Tazarotene} MedChemExpress|{Tazarotene} Autophagy|{Tazarotene} Biological Activity|{Tazarotene} In Vitro|{Tazarotene} supplier|{Tazarotene} Epigenetics} 29|Formula: C10H27N4Na2O16P|Chemical Name: disodium octahydrate [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl phosphate|Smiles: O.{{Ciprofloxacin} medchemexpress|{Ciprofloxacin} Antibiotic|{Ciprofloxacin} Biological Activity|{Ciprofloxacin} Description|{Ciprofloxacin} manufacturer|{Ciprofloxacin} Epigenetics} O.PMID:36014399 O.O.O.O.O.O.[Na+].[Na+].[O-]P([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CNC2=O|InChiKey: QKWLBOYKTJDMLH-NAGQJCCQSA-L|InChi: InChI=1S/C10H13N4O8P.2Na.8H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;;;;;;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;8*1H2/q;2*+1;;;;;;;;/p-2/t4-,6-,7-,10-;;;;;;;;;;/m1………./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

CI 976

by Proton-pump inhibitor Oct 20, 2024

Product Name :
CI 976

Description:
Product information

CAS:
114289-47-3

Molecular Weight:
393.56

Formula:
C23H39NO4

Chemical Name:
2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide

Smiles :
CCCCCCCCCCC(C)(C)C(=O)NC1C(=CC(=CC=1OC)OC)OC

InChiKey:
WAFNZAURAWBNDZ-UHFFFAOYSA-N

InChi :
InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ofatumumab} medchemexpress|{Ofatumumab} CD20|{Ofatumumab} Protocol|{Ofatumumab} In Vitro|{Ofatumumab} supplier|{Ofatumumab} Autophagy}

Shelf Life:
≥12 months if stored properly.{{Phenol Red sodium salt} medchemexpress|{Phenol Red sodium salt} {Fluorescent Dye}|{Phenol Red sodium salt} Biological Activity|{Phenol Red sodium salt} In Vivo|{Phenol Red sodium salt} supplier|{Phenol Red sodium salt} Autophagy}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Product information|CAS Number: 114289-47-3|Molecular Weight: 393.PMID:24278086 56|Formula: C23H39NO4|Chemical Name: 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide|Smiles: CCCCCCCCCCC(C)(C)C(=O)NC1C(=CC(=CC=1OC)OC)OC|InChiKey: WAFNZAURAWBNDZ-UHFFFAOYSA-N|InChi: InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

GSK J5

by Proton-pump inhibitor Oct 20, 2024

Product Name :
GSK J5

Description:
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer.,. GSK-J4 is a cell-permeable prodrug which is modified by intracellular esterases to give GSK-J1, an inhibitor of JMJD3. GSK-J5 is a pyridine regio-isomer of GSK-J4. Like GSK-J4, this isomer is cell-permeable and hydrolyzed to a free base.3 However, the free base is a weak inhibitor of JMJD3 (IC50 > 100 μM), making it an ideal inactive control molecule for elucidating the functional role of JMJD3 inhibition. Reference: . Agger, K., Cloos, P.A.C., Christensen, J., et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nat.Lett. 449(7163), 731-734 (2011). . Hübner, M.R., and Spector, D.L. Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. Cold Spring Harb.Symp.Quant.Biol. 75, 43-49 (2010). . Kruidenier, L., Chung, C.W., Cheng, Z., et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488, 404-408 (2012).

CAS:
1394854-51-3

Molecular Weight:
417.50

Formula:
C24H27N5O2

Chemical Name:
ethyl 3-{[2-(pyridin-3-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoate

Smiles :
CCOC(=O)CCNC1=CC(=NC(=N1)C1=CN=CC=C1)N1CCC2=CC=CC=C2CC1

InChiKey:
LQPGVGSKBNXQDU-UHFFFAOYSA-N

InChi :
InChI=1S/C24H27N5O2/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29/h3-8,12,16-17H,2,9-11,13-15H2,1H3,(H,26,27,28)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer.{{Anti-Mouse IL-1R Antibody} MedChemExpress|{Anti-Mouse IL-1R Antibody} Immunology/Inflammation|{Anti-Mouse IL-1R Antibody} Technical Information|{Anti-Mouse IL-1R Antibody} References|{Anti-Mouse IL-1R Antibody} custom synthesis|{Anti-Mouse IL-1R Antibody} Epigenetic Reader Domain} ,.{{Flucytosine} web|{Flucytosine} Antibiotic|{Flucytosine} Technical Information|{Flucytosine} Description|{Flucytosine} manufacturer|{Flucytosine} Cancer} GSK-J4 is a cell-permeable prodrug which is modified by intracellular esterases to give GSK-J1, an inhibitor of JMJD3.PMID:35991869 GSK-J5 is a pyridine regio-isomer of GSK-J4. Like GSK-J4, this isomer is cell-permeable and hydrolyzed to a free base.3 However, the free base is a weak inhibitor of JMJD3 (IC50 > 100 μM), making it an ideal inactive control molecule for elucidating the functional role of JMJD3 inhibition. Reference: . Agger, K., Cloos, P.A.C., Christensen, J., et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nat.Lett. 449(7163), 731-734 (2011). . Hübner, M.R., and Spector, D.L. Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. Cold Spring Harb.Symp.Quant.Biol. 75, 43-49 (2010). . Kruidenier, L., Chung, C.W., Cheng, Z., et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488, 404-408 (2012).|Product information|CAS Number: 1394854-51-3|Molecular Weight: 417.50|Formula: C24H27N5O2|Chemical Name: ethyl 3-{[2-(pyridin-3-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoate|Smiles: CCOC(=O)CCNC1=CC(=NC(=N1)C1=CN=CC=C1)N1CCC2=CC=CC=C2CC1|InChiKey: LQPGVGSKBNXQDU-UHFFFAOYSA-N|InChi: InChI=1S/C24H27N5O2/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29/h3-8,12,16-17H,2,9-11,13-15H2,1H3,(H,26,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Featured Uncategorized

Licarbazepine

by Proton-pump inhibitor Oct 19, 2024

Product Name :
Licarbazepine

Description:
Product information

CAS:
29331-92-8

Molecular Weight:
254.28

Formula:
C15H14N2O2

Chemical Name:
(9R)-9-hydroxy-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide

Smiles :
NC(=O)N1C2=CC=CC=C2C[C@@H](O)C2=CC=CC=C12

InChiKey:
BMPDWHIDQYTSHX-CQSZACIVSA-N

InChi :
InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m1/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Scopoletin} medchemexpress|{Scopoletin} Apoptosis|{Scopoletin} Purity & Documentation|{Scopoletin} Formula|{Scopoletin} custom synthesis|{Scopoletin} Epigenetics}

Shelf Life:
≥12 months if stored properly.{{Lurbinectedin} medchemexpress|{Lurbinectedin} DNA Alkylator/Crosslinker|{Lurbinectedin} Biological Activity|{Lurbinectedin} Data Sheet|{Lurbinectedin} custom synthesis|{Lurbinectedin} Epigenetic Reader Domain}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23546012

Additional information:
Product information|CAS Number: 29331-92-8|Molecular Weight: 254.28|Formula: C15H14N2O2|Chemical Name: (9R)-9-hydroxy-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide|Smiles: NC(=O)N1C2=CC=CC=C2C[C@@H](O)C2=CC=CC=C12|InChiKey: BMPDWHIDQYTSHX-CQSZACIVSA-N|InChi: InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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A 841720

by Proton-pump inhibitor Oct 19, 2024

Product Name :
A 841720

Description:
A 841720 is a novel non-competitive antagonist of metabotropic glutamate receptor 1 (mGluR1), with an IC50 value of 10.7 nM to 10 µM L-glutamate-induced calcium release at human mGluR1 receptors . Glutamate as the major excitatory neurotransmitter in the central nervous system functions through two types of receptors, ionotropic glutamate receptors and metabotropic glutamate receptors (mGluRs). MGluRs includes group I mGluRs (mGluR1 and mGluR5 receptors), group II (mGluR2 and mGluR3 receptors) and group III (mGluR4, 6, 7, 8 receptors) . In cells, agonist-induced calcium release was concentration-dependently inhibited by A 841720 in a human mGluR5 receptor FLIPR functional assay. But the IC50 value was just 343 nM. In cells expressing recombinant mGluR5 receptors, A 841720 did not block agonist-induced response. In the human mGluR1 receptor FLIPR assay, the log concentration-response curve was shifted by A 841720 at 10 nM to the right. A 841720 at increasing concentrations profoundly reduced the amplitude of L-quisqualate-evoked calcium release. A 841720 at 30 nM reduced the maximal agonist-induced response by 38%. L-quisqualate-induced response was completely abolished by A 841720 at 100 nM . In a water maze test, all rats gradually learned to locate the submerged platform. Treatment with A 841720 significantly slowered rats to find the platform than vehicle control rats. Rats treated with A 841720 at both 30 and 100 µmol/kg doses not only significantly traveled longer distance to find the hidden platform, but also significantly spent longer time to reach the platform .{{Betamethasone} MedChemExpress|{Betamethasone} Apoptosis|{Betamethasone} Technical Information|{Betamethasone} In Vitro|{Betamethasone} supplier|{Betamethasone} Autophagy}

CAS:
869802-58-4

Molecular Weight:
343.45

Formula:
C17H21N5OS

Chemical Name:
5-(azepan-1-yl)-13-(dimethylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.0²,⁷]trideca-1(13),2(7),3,9,11-pentaen-6-one

Smiles :
CN(C)C1C=CN=C2SC3C(=O)N(C=NC=3C2=1)N1CCCCCC1

InChiKey:
GYWGXEGOXODOQU-UHFFFAOYSA-N

InChi :
InChI=1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
A 841720 is a novel non-competitive antagonist of metabotropic glutamate receptor 1 (mGluR1), with an IC50 value of 10.7 nM to 10 µM L-glutamate-induced calcium release at human mGluR1 receptors . Glutamate as the major excitatory neurotransmitter in the central nervous system functions through two types of receptors, ionotropic glutamate receptors and metabotropic glutamate receptors (mGluRs).{{Sirukumab} medchemexpress|{Sirukumab} Interleukin Related|{Sirukumab} Biological Activity|{Sirukumab} Formula|{Sirukumab} supplier|{Sirukumab} Autophagy} MGluRs includes group I mGluRs (mGluR1 and mGluR5 receptors), group II (mGluR2 and mGluR3 receptors) and group III (mGluR4, 6, 7, 8 receptors) .PMID:29844565 In cells, agonist-induced calcium release was concentration-dependently inhibited by A 841720 in a human mGluR5 receptor FLIPR functional assay. But the IC50 value was just 343 nM. In cells expressing recombinant mGluR5 receptors, A 841720 did not block agonist-induced response. In the human mGluR1 receptor FLIPR assay, the log concentration-response curve was shifted by A 841720 at 10 nM to the right. A 841720 at increasing concentrations profoundly reduced the amplitude of L-quisqualate-evoked calcium release. A 841720 at 30 nM reduced the maximal agonist-induced response by 38%. L-quisqualate-induced response was completely abolished by A 841720 at 100 nM . In a water maze test, all rats gradually learned to locate the submerged platform. Treatment with A 841720 significantly slowered rats to find the platform than vehicle control rats. Rats treated with A 841720 at both 30 and 100 µmol/kg doses not only significantly traveled longer distance to find the hidden platform, but also significantly spent longer time to reach the platform .|Product information|CAS Number: 869802-58-4|Molecular Weight: 343.45|Formula: C17H21N5OS|Chemical Name: 5-(azepan-1-yl)-13-(dimethylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.0²,⁷]trideca-1(13),2(7),3,9,11-pentaen-6-one|Smiles: CN(C)C1C=CN=C2SC3C(=O)N(C=NC=3C2=1)N1CCCCCC1|InChiKey: GYWGXEGOXODOQU-UHFFFAOYSA-N|InChi: InChI=1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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1,1,4,4-Tetraphenyl-1,3-butadiene, 99%

by Proton-pump inhibitor Sep 10, 2024

Product Name :
1,1,4,4-Tetraphenyl-1,3-butadiene, 99%

Synonym:

IUPAC Name :
(1,4,4-triphenylbuta-1,3-dien-1-yl)benzene

CAS NO.Selpercatinib :
1450-63-1

Molecular Weight :

Molecular formula:
C28H22

Smiles:
C(C=C(C1=CC=CC=C1)C1=CC=CC=C1)=C(C1=CC=CC=C1)C1=CC=CC=C1

Description:
1,1,4,4-Tetraphenyl-1,3-butadiene is used as a wavelength shifter.Amcenestrant It is also used as an electroluminescent dye, which glows blue with an electroluminescent dye.PMID:24455443

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Chloromethyl methyl sulfide, 94%

by Proton-pump inhibitor Sep 10, 2024

Product Name :
Chloromethyl methyl sulfide, 94%

Synonym:

IUPAC Name :
chloro(methylsulfanyl)methane

CAS NO.:
2373-51-5

Molecular Weight :

Molecular formula:
C2H5ClS

Smiles:
CSCCl

Description:
Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds.Atropine sulfate It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.Lenzilumab g.PMID:23962101 with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent.

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Gadolinium(III) oxide, REacton™, 99.999% (REO)

by Proton-pump inhibitor Sep 10, 2024

Product Name :
Gadolinium(III) oxide, REacton™, 99.999% (REO)

Synonym:

IUPAC Name :
digadolinium(3+) trioxidandiide

CAS NO.:
12064-62-9

Molecular Weight :

Molecular formula:
Gd2O3

Smiles:
[O–].[O–].[O–].[Gd+3].[Gd+3]

Description:
Gadolinium(III) oxide is used as a raw material for various fluorescent compounds, absorption material in atomic reactions, nuclear fuels, magnetic bubble material and screen-sensitivity increasing material. It is also used in glass and electronic industries.Ribociclib It also acts as a neutron shield, a catalyst, a dielectric ceramic and is used for filament coatings, special glasses, lasers, masers and telecommunication.SC209 It also serves as a laboratory reagent.PMID:24761411 It plays an important role as a potential contrast agent for magnetic resonance imaging (MRI).

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Imidazole-2-carboxaldehyde, 97%

by Proton-pump inhibitor Sep 10, 2024

Product Name :
Imidazole-2-carboxaldehyde, 97%

Synonym:

IUPAC Name :
1H-imidazole-2-carbaldehyde

CAS NO.:
10111-08-7

Molecular Weight :

Molecular formula:
C4H4N2O

Smiles:
O=CC1=NC=CN1

Description:
Imidazole-2-carboxaldehyde is a novel protein tyrosine phosphatase 1B (PTP1B) inhibitor with an important application to treat type-2 diabetes.Siponimod It is used in the preparation of tridentate Schiff-base carboxylate-containing ligands by undergoing condensation reaction with amino acids beta-alanine and 2-aminobenzoic acid.Nemolizumab It is also involved in the study of the imidazole-directed allylation of aldimines.PMID:24381199

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Tris(dibenzylideneacetone)dipalladium(0), Pd 21.5% min

by Proton-pump inhibitor Sep 10, 2024

Product Name :
Tris(dibenzylideneacetone)dipalladium(0), Pd 21.5% min

Synonym:

IUPAC Name :
tris(1,5-diphenylpenta-1,4-dien-3-one) dipalladium

CAS NO.:
51364-51-3

Molecular Weight :

Molecular formula:
C51H42O3Pd2

Smiles:
[Pd].[Pd].O=C(C=CC1=CC=CC=C1)C=CC1=CC=CC=C1.O=C(C=CC1=CC=CC=C1)C=CC1=CC=CC=C1.O=C(C=CC1=CC=CC=C1)C=CC1=CC=CC=C1

Description:
Tris(dibenzylideneacetone)dipalladium(0) is the most widely used Pd0 precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. It is used as a catalyst precursor for palladium-catalyzed carbon-nitrogen bond formation, conversion of aryl chlorides, triflates and nonaflates to nitroaromatics.Domperidone monomaleate It is used as catalyst for the synthesis of epoxides, alpha-arylation of ketones, in combination with BINAP for the asymmetric heck arylation of olefins, site-selective benzylic sp3 palladium-catalyzed direct arylation and homoallylic diamination of terminal olefins.Tenofovir alafenamide It also used for palladium-catalyzed one-pot synthesis of tricyclic indolines, in the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles and cross-coupling of aryl halides with aryl boronic acids.PMID:25147652 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Chloropentaamminerhodium(III) chloride, Rh 34.5% min

by Proton-pump inhibitor Sep 10, 2024

Product Name :
Chloropentaamminerhodium(III) chloride, Rh 34.5% min

Synonym:

IUPAC Name :
rhodium(3+) pentaamine trichloride

CAS NO.:
13820-95-6

Molecular Weight :

Molecular formula:
Cl3H15N5Rh

Smiles:
N.Hoechst 33342 N.Enoxaparin N.PMID:23543429 N.N.[Cl-].[Cl-].[Cl-].[Rh+3]

Description:
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Molybdenum etchant

by Proton-pump inhibitor Sep 9, 2024

Product Name :
Molybdenum etchant

Synonym:

IUPAC Name :

CAS NO.:

Molecular Weight :

Molecular formula:

Smiles:

Description:
Naproxen Amlodipine PMID:35116795

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4-(Dimethylamino)antipyrine, 98+%

by Proton-pump inhibitor Sep 9, 2024

Product Name :
4-(Dimethylamino)antipyrine, 98+%

Synonym:

IUPAC Name :
4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one

CAS NO.:
58-15-1

Molecular Weight :

Molecular formula:
C13H17N3O

Smiles:
CN(C)C1=C(C)N(C)N(C1=O)C1=CC=CC=C1

Description:
Methotrexate Metronidazole PMID:26644518

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Benzylideneacetone, 98+%

by Proton-pump inhibitor Sep 9, 2024

Product Name :
Benzylideneacetone, 98+%

Synonym:

IUPAC Name :

CAS NO.:
122-57-6

Molecular Weight :

Molecular formula:

Smiles:

Description:
Benzylideneacetone is used chiefly as a scent in the manufacture of perfume, drugs & electroplating.Zolbetuximab Tozorakimab PMID:23558135

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Di-n-butylmagnesium, 0.5M solution in heptane, AcroSeal™

by Proton-pump inhibitor Sep 9, 2024

Product Name :
Di-n-butylmagnesium, 0.5M solution in heptane, AcroSeal™

Synonym:

IUPAC Name :

CAS NO.:
1191-47-5

Molecular Weight :
138.54

Molecular formula:
C8H18Mg

Smiles:
[Mg++].Asiatic acid CCC[CH2-].Ethambutol dihydrochloride CCC[CH2-]

Description:
PMID:24761411

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Cerium(IV) sulfate hydrate, 98%

by Proton-pump inhibitor Sep 9, 2024

Product Name :
Cerium(IV) sulfate hydrate, 98%

Synonym:

IUPAC Name :
λ⁴-cerium(4+) disulfate

CAS NO.:
95838-16-7

Molecular Weight :

Molecular formula:
CeO8S2

Smiles:
[Ce+4].Tremelimumab [O-]S([O-])(=O)=O.Pexelizumab [O-]S([O-])(=O)=O

Description:
Cerium(IV) sulfate hydrate is used as a general application for chemical intermediate.PMID:23903683 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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3,4-Dichlorobenzeneboronic acid, 97%

by Proton-pump inhibitor Sep 9, 2024

Product Name :
3,4-Dichlorobenzeneboronic acid, 97%

Synonym:

IUPAC Name :
(3,4-dichlorophenyl)boronic acid

CAS NO.:
151169-75-4

Molecular Weight :

Molecular formula:
C6H5BCl2O2

Smiles:
OB(O)C1=CC=C(Cl)C(Cl)=C1

Description:
Fostamatinib Disodium Halofuginone PMID:28038441 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Phenyl vinyl sulfone, 99+%

by Proton-pump inhibitor Sep 8, 2024

Product Name :
Phenyl vinyl sulfone, 99+%

Synonym:

IUPAC Name :
(ethenesulfonyl)benzene

CAS NO.:
5535-48-8

Molecular Weight :

Molecular formula:
C8H8O2S

Smiles:
C=CS(=O)(=O)C1=CC=CC=C1

Description:
Phenyl vinyl sulfone is used as building blocks in the synthesis of a number of organic substances, participate in polymerization reactions, nucleophilic addition reaction, and in cycloaddition reactions.Amsacrine It is also used in the used in the synthesis of reactive dyes, synthesis of textile fibers, in particular cellulose fibers such as cotton and linen.Xanthohumol Other applications in the field of medicine includes as powerful inhibitors of certain enzymatic processes.PMID:22943596 It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuff.

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2,4-Lutidine, 98+%

by Proton-pump inhibitor Sep 8, 2024

Product Name :
2,4-Lutidine, 98+%

Synonym:

IUPAC Name :
2,4-dimethylpyridine

CAS NO.Lansoprazole :
108-47-4

Molecular Weight :

Molecular formula:
C7H9N

Smiles:
CC1=CC=NC(C)=C1

Description:
Enfortumab (anti-Nectin-4) PMID:24118276

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Sodium metaperiodate, ACS, 99.8-100.3%

by Proton-pump inhibitor Sep 8, 2024

Product Name :
Sodium metaperiodate, ACS, 99.8-100.3%

Synonym:

IUPAC Name :
sodium periodate

CAS NO.:
7790-28-5

Molecular Weight :

Molecular formula:
INaO4

Smiles:
[Na+].[O-][I](=O)(=O)=O

Description:
Sodium metaperiodate is used as an oxidizing reagent involved in the oxidation of cellulose.Cefotaxime sodium salt It is involved in the cleavage of vicinal diols to prepare two aldehydes.Orphenadrine citrate This oxidation is commonly used in selectively label RNA, saccharides and other compounds with vicinal diols.PMID:27108903

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N-Boc-iminodiacetic acid, 98%

by Proton-pump inhibitor Sep 8, 2024

Product Name :
N-Boc-iminodiacetic acid, 98%

Synonym:

IUPAC Name :
2-{[(tert-butoxy)carbonyl](carboxymethyl)amino}acetic acid

CAS NO.FIPI :
56074-20-5

Molecular Weight :

Molecular formula:
C9H15NO6

Smiles:
CC(C)(C)OC(=O)N(CC(O)=O)CC(O)=O

Description:
PF-06821497 PMID:23290930

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3-Mercapto-2-pentanone, 97%, stab. with 0.1% Calcium carbonate

by Proton-pump inhibitor Sep 8, 2024

Product Name :
3-Mercapto-2-pentanone, 97%, stab. with 0.1% Calcium carbonate

Synonym:

IUPAC Name :
3-sulfanylpentan-2-one

CAS NO.:
67633-97-0

Molecular Weight :

Molecular formula:
C5H10OS

Smiles:
CCC(S)C(C)=O

Description:
G-1 Icariin PMID:24211511 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Sulfur trioxide trimethylamine complex, 95%

by Proton-pump inhibitor Sep 8, 2024

Product Name :
Sulfur trioxide trimethylamine complex, 95%

Synonym:

IUPAC Name :
sulfonylideneoxidane; trimethylamine

CAS NO.Niraparib hydrochloride :
3162-58-1

Molecular Weight :

Molecular formula:
C3H9NO3S

Smiles:
CN(C)C.Erythrosine B O=S(=O)=O

Description:
PMID:23910527 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Bromine, 1M solution in acetic acid

by Proton-pump inhibitor Sep 8, 2024

Product Name :
Bromine, 1M solution in acetic acid

Synonym:

IUPAC Name :

CAS NO.Emapalumab :
7726-95-6

Molecular Weight :

Molecular formula:

Smiles:

Description:
Datopotamab PMID:24278086 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Adipic acid, 99%

by Proton-pump inhibitor Sep 7, 2024

Product Name :
Adipic acid, 99%

Synonym:

IUPAC Name :
hexanedioic acid

CAS NO.:
124-04-9

Molecular Weight :

Molecular formula:
C6H10O4

Smiles:
OC(=O)CCCCC(O)=O

Description:
Atrasentan Plitidepsin PMID:23341580

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5-Cyanothiophene-2-carboxaldehyde, 95%

by Proton-pump inhibitor Sep 7, 2024

Product Name :
5-Cyanothiophene-2-carboxaldehyde, 95%

Synonym:

IUPAC Name :
5-nitrothiophene-2-carbaldehyde

CAS NO.:
21512-16-3

Molecular Weight :

Molecular formula:
C5H3NO3S

Smiles:
[O-][N+](=O)C1=CC=C(S1)C=O

Description:
5-Cyanothiophene-2-carboxaldehyde is found in caper and may have pest control activity against meloidogyne incognita.Romosozumab Salmeterol PMID:23558135

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4-Nitrophenyl acetate, 97%

by Proton-pump inhibitor Sep 7, 2024

Product Name :
4-Nitrophenyl acetate, 97%

Synonym:

IUPAC Name :
4-nitrophenyl acetate

CAS NO.Polatuzumab vedotin :
830-03-5

Molecular Weight :

Molecular formula:
C8H7NO4

Smiles:
CC(=O)OC1=CC=C(C=C1)[N+]([O-])=O

Description:
4-Nitrophenyl acetate is used with iodoacetic acid for reductive cleavage of methionine-containing peptides.Pitavastatin Calcium It is also used as a substrate that has been used in assays for esterase and lipase activity.PMID:23489613 Inorganic complexes have been evaluated for their methanolysis or hydrolysis activity using p-nitrophenyl acetate.

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2-(1-Piperazinyl)pyrimidine, 98+%

by Proton-pump inhibitor Sep 7, 2024

Product Name :
2-(1-Piperazinyl)pyrimidine, 98+%

Synonym:

IUPAC Name :
2-(piperazin-1-yl)pyrimidine

CAS NO.:
20980-22-7

Molecular Weight :

Molecular formula:
C8H12N4

Smiles:
C1CN(CCN1)C1=NC=CC=N1

Description:
Spermine Aramisulpride PMID:27108903

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Potassium hexachloroiridate(III) hydrate, Ir 32.8% min

by Proton-pump inhibitor Sep 7, 2024

Product Name :
Potassium hexachloroiridate(III) hydrate, Ir 32.8% min

Synonym:

IUPAC Name :

CAS NO.:

Molecular Weight :

Molecular formula:

Smiles:

Description:
Potassium hexachloroiridate(III) hydrate is used to prepare other iridium compounds.Dihexa It is used as a redox mediator to visualize human finger prints on a poly(vinylidene difluoride) membrane by scanning electrochemical microscopy.Opipramol PMID:26895888 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Cesium bromide, ultra dry, 99.9% (metals basis)

by Proton-pump inhibitor Sep 7, 2024

Product Name :
Cesium bromide, ultra dry, 99.9% (metals basis)

Synonym:

IUPAC Name :
caesium(1+) bromide

CAS NO.Ristocetin :
7787-69-1

Molecular Weight :

Molecular formula:
BrCs

Smiles:
[Br-].Vilazodone [Cs+]

Description:
Cesium bromide is used as reagent, intermediate in pharmaceuticals.PMID:24605203 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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1,1,1-Trifluoro-2,4-pentanedione, 98%

by Proton-pump inhibitor Sep 7, 2024

Product Name :
1,1,1-Trifluoro-2,4-pentanedione, 98%

Synonym:

IUPAC Name :

CAS NO.A-966492 :
367-57-7

Molecular Weight :

Molecular formula:

Smiles:

Description:
1,1,1-Trifluoro-2,4-pentanedione has been used as reagent in the preparation of 2-alkylcarbonyl and 2-benzoyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives.Leukotriene C4 PMID:24957087 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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DL-Norleucine, 98%

by Proton-pump inhibitor Sep 6, 2024

Product Name :
DL-Norleucine, 98%

Synonym:

IUPAC Name :
2-aminohexanoic acid

CAS NO.Ixekizumab :
616-06-8

Molecular Weight :

Molecular formula:
C6H13NO2

Smiles:
CCCCC(N)C(O)=O

Description:
Inolimomab PMID:32926338

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Copper(II) nitrate trihydrate, 99%, for analysis

by Proton-pump inhibitor Sep 6, 2024

Product Name :
Copper(II) nitrate trihydrate, 99%, for analysis

Synonym:

IUPAC Name :
copper(2+) dinitrate

CAS NO.Arbekacin :
10031-43-3

Molecular Weight :

Molecular formula:
CuN2O6

Smiles:
[Cu++].Ranolazine [O-][N+]([O-])=O.PMID:24179643 [O-][N+]([O-])=O

Description:

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Iridium black, 99.8% (metals basis)

by Proton-pump inhibitor Sep 6, 2024

Product Name :
Iridium black, 99.8% (metals basis)

Synonym:

IUPAC Name :
iridium

CAS NO.:
7439-88-5

Molecular Weight :

Molecular formula:
Ir

Smiles:
[Ir]

Description:
The primary use of iridium is as a hardening agent in platinum alloys.Phenytoin Other uses are for the making of crucibles and devices that require high temperatures.Omaveloxolone Osmium/iridium alloys are used for compass bearings.PMID:36628218 Iridium is commonly used in complexes like Ir(mppy)3 and other complexes in polymer LED technology to increase the efficiency from 25% to about 100% due to triplet harvesting. Used in high-dose radiation therapy for the treatment of prostate and other forms of cancer. Iridium is used in tips of ballpoint pens. Iridium is used as a catalyst for carbonylation of methanol to create acetic acid. At one time, iridium as an alloy with platinum, was used in bushing the vents of heavy ordnance and, in a finely powdered condition (iridium black) for painting porcelain black.

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(R)-2-Amino-7-hydroxytetralin, 97%

by Proton-pump inhibitor Sep 6, 2024

Product Name :
(R)-2-Amino-7-hydroxytetralin, 97%

Synonym:

IUPAC Name :

CAS NO.:
85951-61-7

Molecular Weight :

Molecular formula:

Smiles:

Description:
4-Thiouridine Cefditoren (Pivoxil) PMID:34645436

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Calcium chloride, ultra dry, 99.99% (metals basis)

by Proton-pump inhibitor Sep 6, 2024

Product Name :
Calcium chloride, ultra dry, 99.99% (metals basis)

Synonym:

IUPAC Name :
calcium dichloride

CAS NO.:
10043-52-4

Molecular Weight :

Molecular formula:
CaCl2

Smiles:
[Cl-].[Cl-].[Ca++]

Description:
Calcium chloride is used as a drying and dehydrating agent for organic liquids and gases and for solids in desiccators. Common applications include brine for refrigeration plants and ice and dust control on roads. Use of calcium chloride and urea has been reported to significantly increase average fruit weight and ascorbic acid content in pomegranates. The strawberry fruit storability can also be improved by edible coating of calcium chloride. It is used in drying tubes in research laboratories, salt/chemical based dehumidifiers, fire-extinguishers, plastics, ceramic slipware, as flux in the Davy process for the manufacture of sodium and to increase water hardness in swimming pool.Exicorilant It provides inhibition of swelling clays in the water phase of invert emulsion drilling fluids.Triheptanoin CaCl2-Pybox (pyridine flanked by two oxazoline groups) has been reported to be an efficient chiral catalyst for asymmetric 1,4-addition reactions of 1,3-dicarbonyl compounds with nitroalkenes, affording gamma-nitro carbonyl compounds in high enantioselectivities.PMID:23724934 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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by Proton-pump inhibitor Aug 30, 2024

Product Name :
Terbium(III) chloride hexahydrate, 99.9%, (trace metal basis)

Synonym:

IUPAC Name :
terbium(3+) hexahydrate trichloride

CAS NO.AK-7 :
13798-24-8

Molecular Weight :

Molecular formula:
Cl3H12O6Tb

Smiles:
O.Esomeprazole O.PMID:28739548 O.O.O.O.[Cl-].[Cl-].[Cl-].[Tb+3]

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2,3-Dichlorobenzoyl chloride, 98%

by Proton-pump inhibitor Aug 29, 2024

Product Name :
2,3-Dichlorobenzoyl chloride, 98%

Synonym:

IUPAC Name :

CAS NO.:
2905-60-4

Molecular Weight :

Molecular formula:

Smiles:

Description:
α-Hemolysin (Staphylococcus aureus) Anti-Mouse CD8a Antibody PMID:23551549

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Y5

by Proton-pump inhibitor Aug 29, 2024

Product Name :
Y5

Synonym:

IUPAC Name :

CAS NO.:
2304444-48-0

Molecular Weight :

Molecular formula:

Smiles:

Description:
Vigabatrin Teniposide PMID:23865629

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N-Ethylmaleimide, 98+%

by Proton-pump inhibitor Aug 29, 2024

Product Name :
N-Ethylmaleimide, 98+%

Synonym:

IUPAC Name :
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione

CAS NO.:
128-53-0

Molecular Weight :

Molecular formula:
C6H7NO2

Smiles:
CCN1C(=O)C=CC1=O

Description:
Fenebrutinib Tacrine PMID:24238102

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Selenium(IV) oxide, Puratronic™, 99.999% (metals basis)

by Proton-pump inhibitor Aug 29, 2024

Product Name :
Selenium(IV) oxide, Puratronic™, 99.999% (metals basis)

Synonym:

IUPAC Name :
(oxo-λ⁴-selanylidene)oxidane

CAS NO.:
7446-08-4

Molecular Weight :

Molecular formula:
O2Se

Smiles:
O=[Se]=O

Description:
In organic reactions, selenium dioxide is often used as an oxidizing reagent employed for carrying out allylic oxidations, Riley oxidation, synthesis of diones, etc.Otamixaban It is used to impart a red color to glass.Galcuronokinase It finds use as a toner in photographic developing, and an active ingredient in some cold-blueing solutions.PMID:24818938

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Tungsten silicide, 99.5% (metals basis)

by Proton-pump inhibitor Aug 29, 2024

Product Name :
Tungsten silicide, 99.5% (metals basis)

Synonym:

IUPAC Name :
tungsten disilicide

CAS NO.:
12039-88-2

Molecular Weight :

Molecular formula:
Si2W

Smiles:
[Si]#[W]#[Si]

Description:
Tungsten silicide is used in microelectronics as a contact material.Zoledronic Acid It is also used as a shunt over polysilicon lines to increase their conductivity and increase signal speed.Miconazole Further, it acts as a barrier layer between silicon and other metals.PMID:25959043 In addition to this, it is used in microelectro mechanical systems and for oxidation-resistant coatings. It is also employed as a replacement for earlier tungsten films.MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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N-Formylpiperidine, 99%

by Proton-pump inhibitor Aug 29, 2024

Product Name :
N-Formylpiperidine, 99%

Synonym:

IUPAC Name :
piperidine-1-carbaldehyde

CAS NO.:
2591-86-8

Molecular Weight :

Molecular formula:
C6H11NO

Smiles:
O=CN1CCCCC1

Description:
Clofibrate Biotin Hydrazide PMID:23789847 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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2-Methylcyclohexylamine, cis + trans, 97%

by Proton-pump inhibitor Aug 28, 2024

Product Name :
2-Methylcyclohexylamine, cis + trans, 97%

Synonym:

IUPAC Name :

CAS NO.:
7003-32-9

Molecular Weight :

Molecular formula:

Smiles:

Description:
2-Methylcyclohexylamine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.Bromothymol Blue E260 PMID:23996047

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1-Methylindole-2-carboxylic acid

by Proton-pump inhibitor Aug 28, 2024

Product Name :
1-Methylindole-2-carboxylic acid

Synonym:

IUPAC Name :
1-methyl-1H-indole-2-carboxylic acid

CAS NO.:
16136-58-6

Molecular Weight :

Molecular formula:
C10H9NO2

Smiles:
CN1C(=CC2=CC=CC=C12)C(O)=O

Description:
Metformin hydrochloride Ledipasvir PMID:23398362

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Glass beads, 1 mm

by Proton-pump inhibitor Aug 28, 2024

Product Name :
Glass beads, 1 mm

Synonym:

IUPAC Name :

CAS NO.4-Methylumbelliferone :

Molecular Weight :

Molecular formula:

Smiles:

Description:
DAPT PMID:23600560

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Potassium antimonate trihydrate, 94+%

by Proton-pump inhibitor Aug 28, 2024

Product Name :
Potassium antimonate trihydrate, 94+%

Synonym:

IUPAC Name :
antimony(3+) potassium hexahydroxide

CAS NO.:
12208-13-8

Molecular Weight :

Molecular formula:
H6KO6Sb

Smiles:
[OH-].Anti-Mouse PD-1 Antibody [OH-].[OH-].[OH-].[OH-].[OH-].[K+].[Sb+3]

Description:
Potassium antimonyl trihydrate is used as a detecting agent for sodium.Florfenicol It is used as a mordant/ fixing agent in leather and textile dying industries.PMID:26895888 It is also used as a analytical reagent and flux additive for electroplating.

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4-Biphenylacetonitrile, 97%

by Proton-pump inhibitor Aug 28, 2024

Product Name :
4-Biphenylacetonitrile, 97%

Synonym:

IUPAC Name :

CAS NO.:
31603-77-7

Molecular Weight :

Molecular formula:

Smiles:

Description:
Aflatoxin M1 Nicotinamide N-Methyltransferase/NNMT, Human (His) PMID:23554582 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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2,4-Dihydroxybenzoic acid, 97%

by Proton-pump inhibitor Aug 28, 2024

Product Name :
2,4-Dihydroxybenzoic acid, 97%

Synonym:

IUPAC Name :
2,4-dihydroxybenzoic acid

CAS NO.:
89-86-1

Molecular Weight :

Molecular formula:
C7H6O4

Smiles:
OC(=O)C1=CC=C(O)C=C1O

Description:
2,4-Dihydroxybenzoic acid is used in Intermediates, Plasticizers, Plastic and Rubber Products, a organic building block.Lansoprazole Bimagrumab PMID:24220671 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Dichloromethane, 99.9%, Extra Dry, anhydrous, SC, AcroSeal™

by Proton-pump inhibitor Aug 27, 2024

Product Name :
Dichloromethane, 99.9%, Extra Dry, anhydrous, SC, AcroSeal™

Synonym:

IUPAC Name :
dichloromethane

CAS NO.:
75-09-2

Molecular Weight :

Molecular formula:
CH2Cl2

Smiles:
ClCCl

Description:
Ipratropium bromide Venetoclax PMID:24268253

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4-Bromobenzamide, 97%

by Proton-pump inhibitor Aug 27, 2024

Product Name :
4-Bromobenzamide, 97%

Synonym:

IUPAC Name :
4-bromobenzamide

CAS NO.:
698-67-9

Molecular Weight :

Molecular formula:
C7H6BrNO

Smiles:
NC(=O)C1=CC=C(Br)C=C1

Description:
Nedaplatin Tylosin PMID:24818938

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N,N’-Bis(salicylidene)ethylenediamine, 98%

by Proton-pump inhibitor Aug 27, 2024

Product Name :
N,N’-Bis(salicylidene)ethylenediamine, 98%

Synonym:

IUPAC Name :
(6Z)-6-({[2-({[(1Z)-6-oxocyclohexa-2,4-dien-1-ylidene]methyl}amino)ethyl]amino}methylidene)cyclohexa-2,4-dien-1-one

CAS NO.Betaxolol :
94-93-9

Molecular Weight :

Molecular formula:
C16H16N2O2

Smiles:
O=C1C=CC=C\C1=C\NCCN\C=C1\C=CC=CC1=O

Description:
Salicylic acid PMID:25105126

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4-Nitro-3-(trifluoromethyl)phenol, 97%

by Proton-pump inhibitor Aug 27, 2024

Product Name :
4-Nitro-3-(trifluoromethyl)phenol, 97%

Synonym:

IUPAC Name :
4-nitro-3-(trifluoromethyl)phenol

CAS NO.:
88-30-2

Molecular Weight :

Molecular formula:
C7H4F3NO3

Smiles:
OC1=CC=C(C(=C1)C(F)(F)F)[N+]([O-])=O

Description:
Fluorescein FH1 PMID:23746961

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(±)-Mandelic Acid, 99%

by Proton-pump inhibitor Aug 27, 2024

Product Name :
(±)-Mandelic Acid, 99%

Synonym:

IUPAC Name :
2-hydroxy-2-phenylacetic acid

CAS NO.:
90-64-2

Molecular Weight :

Molecular formula:
C8H8O3

Smiles:
OC(C(O)=O)C1=CC=CC=C1

Description:
Mandelic acid is used in the pharmaceutical industry as an antibacterial to treat urinary tract infections. It acts as a precursor for making various drugs. It is also used as an oral antibiotic. Mandelic acid peels are widely used for treating damaged skin due to its less penetrating and irritating property.Drotaverine (hydrochloride) Enantiomeric resolution of (±)-Mandelic acid is performed by using the chiral amine (1R,2S)-(-)-ephedrine followed by acidification to prepare (R)-( -)-Mandelic acid.Ceftaroline fosamil PMID:26780211 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Iron(III) meso-tetraphenylporphine-mu-oxo dimer

by Proton-pump inhibitor Aug 27, 2024

Product Name :
Iron(III) meso-tetraphenylporphine-mu-oxo dimer

Synonym:

IUPAC Name :
bis(λ²-iron(2+)) bis(2,7,12,17-tetraphenyl-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaene-21,23-diide) hydrate

CAS NO.:
12582-61-5

Molecular Weight :

Molecular formula:
C88H58Fe2N8O

Smiles:
O.[Fe++].[Fe++].[N-]1C2=CC=C1C(=C1C=CC(=N1)C(=C1[N-]C(C=C1)=C(C1=NC(C=C1)=C2C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1.Ambrisentan [N-]1C2=CC=C1C(=C1C=CC(=N1)C(=C1[N-]C(C=C1)=C(C1=NC(C=C1)=C2C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1

Description:
Iron(III) meso-tetraphenylporphine-μ-oxo dimer used as catalyst.Ensitrelvir PMID:24360118 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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D(+)-Camphor, 97%

by Proton-pump inhibitor Aug 26, 2024

Product Name :
D(+)-Camphor, 97%

Synonym:

IUPAC Name :
(1R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

CAS NO.:
464-49-3

Molecular Weight :

Molecular formula:
C10H16O

Smiles:
CC1(C)[C@H]2CC[C@@]1(C)C(=O)C2

Description:
Polymyxin B Sulfate Exicorilant PMID:25023702

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(2S,4S)-1-Boc-4-diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine

by Proton-pump inhibitor Aug 26, 2024

Product Name :
(2S,4S)-1-Boc-4-diphenylphosphino-2-(diphenylphosphinomethyl)pyrrolidine

Synonym:

IUPAC Name :

CAS NO.Clazosentan :

Molecular Weight :

Molecular formula:

Smiles:

Description:
XT2 PMID:25023702

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4-Methyl-1,2,3-thiadiazole-5-carboxylic acid, 98%

by Proton-pump inhibitor Aug 26, 2024

Product Name :
4-Methyl-1,2,3-thiadiazole-5-carboxylic acid, 98%

Synonym:

IUPAC Name :

CAS NO.:
18212-21-0

Molecular Weight :

Molecular formula:

Smiles:

Description:
Gossypol Decitabine PMID:24238102

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Osmium, plasma standard solution, Specpure™ Os 1000μg/mL

by Proton-pump inhibitor Aug 26, 2024

Product Name :
Osmium, plasma standard solution, Specpure™ Os 1000μg/mL

Synonym:

IUPAC Name :

CAS NO.:

Molecular Weight :

Molecular formula:

Smiles:

Description:
Osmium, plasma standard solution is used as a standard solution in analytical chemistry and atomic absorption spectroscopy.Biperiden It is also used as a single-element standard solution for plasma emission spectrometry.Etrolizumab PMID:23672196 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Phenylphosphonic dichloride, 97%

by Proton-pump inhibitor Aug 26, 2024

Product Name :
Phenylphosphonic dichloride, 97%

Synonym:

IUPAC Name :
phenylphosphonoyl dichloride

CAS NO.Quavonlimab :
824-72-6

Molecular Weight :

Molecular formula:
C6H5Cl2OP

Smiles:
ClP(Cl)(=O)C1=CC=CC=C1

Description:
Didox PMID:24455443 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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1,2-Diiodoethane, 99%

by Proton-pump inhibitor Aug 25, 2024

Product Name :
1,2-Diiodoethane, 99%

Synonym:

IUPAC Name :
1,2-diiodoethane

CAS NO.Sitravatinib :
624-73-7

Molecular Weight :

Molecular formula:
C2H4I2

Smiles:
ICCI

Description:
Letermovir PMID:23008002

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3-Chloro-4-hydroxybenzonitrile, 95%

by Proton-pump inhibitor Aug 25, 2024

Product Name :
3-Chloro-4-hydroxybenzonitrile, 95%

Synonym:

IUPAC Name :
3-chloro-4-hydroxybenzonitrile

CAS NO.:
2315-81-3

Molecular Weight :

Molecular formula:
C7H4ClNO

Smiles:
OC1=CC=C(C=C1Cl)C#N

Description:
Axatilimab Hispidulin PMID:23381626

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Hydrochloric acid, 0.01N Standardized Solution

by Proton-pump inhibitor Aug 25, 2024

Product Name :
Hydrochloric acid, 0.01N Standardized Solution

Synonym:

IUPAC Name :
hydrogen chloride

CAS NO.Fmoc-Asn(Trt)-OH :
7647-01-0

Molecular Weight :

Molecular formula:
ClH

Smiles:
Cl

Description:
Hydrochloric acid, 0.Nitroxoline 01N standardized solution is used for volumetric analysis in laboratories.PMID:24367939

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2-Aminoimidazole hemisulfate, 98+%

by Proton-pump inhibitor Aug 25, 2024

Product Name :
2-Aminoimidazole hemisulfate, 98+%

Synonym:

IUPAC Name :
bis(1H-imidazol-2-amine); sulfuric acid

CAS NO.:
1450-93-7

Molecular Weight :

Molecular formula:
C6H12N6O4S

Smiles:
OS(O)(=O)=O.Eflornithine NC1=NC=CN1.7-Amino-4-methylcoumarin NC1=NC=CN1

Description:
PMID:23865629 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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2,3-Dimethylphenylhydrazine hydrochloride, 97%

by Proton-pump inhibitor Aug 25, 2024

Product Name :
2,3-Dimethylphenylhydrazine hydrochloride, 97%

Synonym:

IUPAC Name :
(2,3-dimethylphenyl)hydrazine hydrochloride

CAS NO.:
56737-75-8

Molecular Weight :

Molecular formula:
C8H13ClN2

Smiles:
Cl.J-147 CC1=C(C)C(NN)=CC=C1

Description:
Permethrin PMID:23746961 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Aluminum oxide, activated, neutral, Brockmann Grade II

by Proton-pump inhibitor Aug 25, 2024

Product Name :
Aluminum oxide, activated, neutral, Brockmann Grade II

Synonym:

IUPAC Name :
dialuminium(3+) trioxidandiide

CAS NO.:
1344-28-1

Molecular Weight :

Molecular formula:
Al2O3

Smiles:
[O–].[O–].[O–].[Al+3].[Al+3]

Description:
Aluminum oxide is used as an abrasive, dosimeter, filler of choice for plastics, ingredient in sunscreen and cosmetics. Aluminum oxide flakes are also used in paint for providing reflective decorative effects. In laboratories it is widely used as a medium for chromatographic purifications. It is used in the production of aluminum (Hall–Héroult process), alumina nanofibers, cutoff tools, and sandpaper. It serves as a catalyst for several reactions of industrial importance, including converting alcohols into alkenes, decomposing hydrazine, drying of gases, and converting hydrogen sulfide into sulfur in refineries (Claus Process).Sintilimab It is also used in integrated circuits, compact fluorescent lamps (CFL), sodium vapor lamps, hip replacements, CD/DVD polishing, superconducting quantum interference devices (SQUIDS), insulation devices, and as a support for many popular catalysts (for example, in Ziegler-Natta polymerizations).Blinatumomab PMID:24423657 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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trans-4-Hydroxy-L-proline, 99+%

by Proton-pump inhibitor Aug 24, 2024

Product Name :
trans-4-Hydroxy-L-proline, 99+%

Synonym:

IUPAC Name :
4-hydroxypyrrolidine-2-carboxylic acid

CAS NO.:
51-35-4

Molecular Weight :

Molecular formula:
C5H9NO3

Smiles:
OC1CNC(C1)C(O)=O

Description:
Sulfasalazine Punicalagin PMID:23927631

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Ethyl isobutyrylacetate, 94%

by Proton-pump inhibitor Aug 24, 2024

Product Name :
Ethyl isobutyrylacetate, 94%

Synonym:

IUPAC Name :
ethyl 4-methyl-3-oxopentanoate

CAS NO.:
7152-15-0

Molecular Weight :

Molecular formula:
C8H14O3

Smiles:
CCOC(=O)CC(=O)C(C)C

Description:
Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties .Nicotinamide N-Methyltransferase/NNMT, Human (His) Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity.Besifovir PMID:35954127

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5-Chloro-2-hydroxybenzamide, 97%

by Proton-pump inhibitor Aug 24, 2024

Product Name :
5-Chloro-2-hydroxybenzamide, 97%

Synonym:

IUPAC Name :

CAS NO.:

Molecular Weight :

Molecular formula:

Smiles:

Description:
Quinidine Doxycycline PMID:23319057

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Rhodium 10%, Palladium 1% on activated carbon powder

by Proton-pump inhibitor Aug 24, 2024

Product Name :
Rhodium 10%, Palladium 1% on activated carbon powder

Synonym:

IUPAC Name :

CAS NO.(-)-Blebbistatin :

Molecular Weight :

Molecular formula:

Smiles:

Description:
Tenofovir alafenamide PMID:23912708

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Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylate, 97%

by Proton-pump inhibitor Aug 24, 2024

Product Name :
Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylate, 97%

Synonym:

IUPAC Name :
ethyl 5-tert-butyl-1H-pyrazole-3-carboxylate

CAS NO.:
916791-97-4

Molecular Weight :

Molecular formula:
C10H16N2O2

Smiles:
CCOC(=O)C1=NNC(=C1)C(C)(C)C

Description:
Ethyl 3-tert-butyl-1H-pyrazole-5-carboxylate is used as pharmaceutical intermediates.Methoprene Pyridostigmine bromide PMID:33679749 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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4-Methoxybenzyl isocyanate, 99%

by Proton-pump inhibitor Aug 24, 2024

Product Name :
4-Methoxybenzyl isocyanate, 99%

Synonym:

IUPAC Name :
1-(isocyanatomethyl)-4-methoxybenzene

CAS NO.:
56651-60-6

Molecular Weight :

Molecular formula:
C9H9NO2

Smiles:
COC1=CC=C(CN=C=O)C=C1

Description:
IL-2 Protein, Mouse Vilazodone Hydrochloride PMID:24670464 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Boric acid, Molecular Biology Grade, 99.5% min

by Proton-pump inhibitor Aug 24, 2024

Product Name :
Boric acid, Molecular Biology Grade, 99.5% min

Synonym:

IUPAC Name :
boric acid

CAS NO.:
10043-35-3

Molecular Weight :

Molecular formula:
BH3O3

Smiles:
OB(O)O

Description:
Used to promote amidations of carboxylic acids and amines in catalytic amounts.Ciclopirox olamine LM10 PMID:23290930 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Platinum sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick, 99.99% (metals basis)

by Proton-pump inhibitor Aug 23, 2024

Product Name :
Platinum sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick, 99.99% (metals basis)

Synonym:

IUPAC Name :

CAS NO.Anti-Mouse CD8a Antibody :
7440-06-4

Molecular Weight :

Molecular formula:

Smiles:

Description:
Tezepelumab PMID:23880095

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Di-n-butylamine, 99%

by Proton-pump inhibitor Aug 23, 2024

Product Name :
Di-n-butylamine, 99%

Synonym:

IUPAC Name :
dibutylamine

CAS NO.:
111-92-2

Molecular Weight :

Molecular formula:
C8H19N

Smiles:
CCCCNCCCC

Description:
Combretastatin A4 Deruxtecan PMID:23357584

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Perfluorononane, 99%

by Proton-pump inhibitor Aug 23, 2024

Product Name :
Perfluorononane, 99%

Synonym:

IUPAC Name :

CAS NO.:
375-96-2

Molecular Weight :

Molecular formula:

Smiles:

Description:
Natalizumab (Solution) Demeclocycline hydrochloride PMID:23319057

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Glycerol, pure, 83.5-88.5 wt% aqueous solution

by Proton-pump inhibitor Aug 23, 2024

Product Name :
Glycerol, pure, 83.5-88.5 wt% aqueous solution

Synonym:

IUPAC Name :
propane-1,2,3-triol

CAS NO.:
56-81-5

Molecular Weight :

Molecular formula:
C3H8O3

Smiles:
OCC(O)CO

Description:
Telitacicept Cediranib maleate PMID:28322188

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1-Dimethylamino-2-propanol, 99%

by Proton-pump inhibitor Aug 23, 2024

Product Name :
1-Dimethylamino-2-propanol, 99%

Synonym:

IUPAC Name :
1-(dimethylamino)propan-2-ol

CAS NO.:
108-16-7

Molecular Weight :

Molecular formula:
C5H13NO

Smiles:
CC(O)CN(C)C

Description:
Bazedoxifene Voxelotor PMID:26780211 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Ritalinic acid

by Proton-pump inhibitor Aug 23, 2024

Product Name :
Ritalinic acid

Synonym:

IUPAC Name :
2-phenyl-2-(piperidin-2-yl)acetic acid

CAS NO.AR7 :
19395-41-6

Molecular Weight :

Molecular formula:
C13H17NO2

Smiles:
OC(=O)C(C1CCCCN1)C1=CC=CC=C1

Description:
Belantamab PMID:23557924 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

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Pyrene, 98%

by Proton-pump inhibitor Aug 22, 2024

Product Name :
Pyrene, 98%

Synonym:

IUPAC Name :
pyrene

CAS NO.:
129-00-0

Molecular Weight :

Molecular formula:
C16H10

Smiles:
C1=CC2=CC=C3C=CC=C4C=CC(=C1)C2=C34

Description:
Niraparib Polatuzumab vedotin PMID:24456950

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Aluminum rod, alloy 6061, 25.4mm (1.0in) dia

by Proton-pump inhibitor Aug 22, 2024

Product Name :
Aluminum rod, alloy 6061, 25.4mm (1.0in) dia

Synonym:

IUPAC Name :

CAS NO.:

Molecular Weight :

Molecular formula:

Smiles:

Description:
Methylprednisolone succinate Sonidegib PMID:24507727

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3-Bromo-4-fluorobenzyl bromide, 97%

by Proton-pump inhibitor Aug 22, 2024

Product Name :
3-Bromo-4-fluorobenzyl bromide, 97%

Synonym:

IUPAC Name :

CAS NO.Nelarabine :
78239-71-1

Molecular Weight :

Molecular formula:

Smiles:

Description:
3-Bromo-4-fluorobenzyl bromide is used as a pharmaceutical intermediate.C6 Ceramide PMID:23443926

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n-Dodecyltriethoxysilane, 95%

by Proton-pump inhibitor Aug 22, 2024

Product Name :
n-Dodecyltriethoxysilane, 95%

Synonym:

IUPAC Name :
dodecyltriethoxysilane

CAS NO.Kahweol :
18536-91-9

Molecular Weight :

Molecular formula:
C18H40O3Si

Smiles:
CCCCCCCCCCCC[Si](OCC)(OCC)OCC

Description:
Etoposide phosphate PMID:35345980

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by Proton-pump inhibitor May 29, 2023

ssion, we first analyzed the gene ontology from the 37 genes that exhibit modifications in expression within the offspring of stressed parents in all four GSK-3α medchemexpress species using g:Profiler (Raudvere et al., 2019). We found that these 37 genes had been considerably enriched for extracellular proteins (p two.278 10). Even so, no more commonalities were identified and none of these 37 genes have previously been linked to adaptations to P. vranovensis infection or osmotic stress. We identified that unique species exhibit unique intergenerational responses to each P. vranovensis infection and osmotic strain (Figure 1). We hypothesized that the effects of parental exposure to environmental stresses on offspring gene expression may possibly correlate with how offspring phenotypically respond to anxiety. Parental exposure of C. elegans and C. kamaaina to P. vranovensis led to improved progeny resistance to future P. vranovensis exposure (Figure 1B). By contrast, parental exposure of C. briggsae to P. vranovensis led to increased offspring susceptibility to P. vranovensis (Figure 1B). We hypothesized that differences within the expression of genes previously reported to become essential for adaptation to P. vranovensis, which include the acyltransferase rhy-1, could underlie these differences among species. We consequently investigated irrespective of whether any genes exhibited distinct adjustments in expression in C. elegans and C. kamaaina that were either absent or inverted in C. briggsae. We identified that with the 562 genes that exhibited a higher than twofold change in expression within the offspring of parents exposed to P. vranovensis in C. elegans, only 54 also exhibited a higher than twofold intergenerational adjust in expression in C. kamaaina (Supplementary file 2). From this refined list of 54 genes, 17 genes either didn’t exhibit a alter in C. briggsae or changed in the opposite path (Table 2). Constant with our hypothesis that intergenerational gene expression adjustments across species may possibly correlate with their phenotypic responses, we found that all 3 genes previously reported to become essential for the intergenerational adaptation to P. vranovensis (rhy-1, cysl-1, and cysl-2 Burton et al., 2020) were among the 17 genes that exhibited differential expression in C. elegans and C.Burton et al. eLife 2021;10:e73425. DOI: doi.org/10.7554/eLife.7 ofResearch articleEvolutionary Biology | Genetics and GenomicsTable 1. Comprehensive list of genes that exhibited a greater than twofold change in expression in the F1 progeny of parents exposed to P. vranovensis or osmotic tension in all 4 species tested.Genes that transform in F1 progeny of all species exposed to P. vranovensis C18A11.1 R13A1.5 D1053.3 pmp-5 C39E9.8 nit-1 lips-10 srr-6 Y51B9A.six gst-33 ptr-8 ZC443.1 cri-2 Y42G9A.three ttr-21 F45E4.5 C42D4.1 asp-14 cyp-32B1 nas-10 W01F3.2 nhr-11 F26G1.two F48E3.2 hpo-26 R05H10.1 C08E8.4 C11G10.1 Y73F4A.two bigr-1 nlp-33 far-Predicted function ACAT2 review Unknown Unknown Unknown ATP-binding activity and ATPase-coupled transmembrane transporter activity, ortholog of human ABCD4 Unknown Nitrilase ortholog predicted to enable hydrolase activity Lipase connected Serpentine receptor, class R Predicted to enable transmembrane transporter activity Glutathione S-transferase Patched domain containing, ortholog of human PTCHD1, PTCHD3, and PTCHD4 Predicted to enable D-threo-aldose 1-dehydrogenase activity Conserved regulator of innate immunity, ortholog of human TIMP2 Unknown Transthyretin-related, involved in response to Gram-negative bac